YONDELIS J Code: J9352

Drug & Product Overview

HCPCS Descriptor Injection, trabectedin, 0.1 mg

HCPCS Added Date January 1, 2017

Manufacturer Janssen

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution

About YONDELIS

Yondelis is a medication aligned to the HCPCS J Code: J9352 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the intravenous route and manufactured by Janssen.

According to CMS Drug Use Information: Trabectedin is used to treat certain types of cancer. It is a chemotherapy drug that works by slowing the growth of cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
59676-0610-01	Yondelis	Janssen Products, LP	10	1 MG / 20 ML

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YONDELIS Pricing & Reimbursement

J9352 Private Payer Reimbursement

$405.81 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

YONDELIS Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 13.25%

Avg. Days to File 11.4days

Avg. Days to Pay 28.5days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J9352 claims analytics on FocalPoint →

YONDELIS CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Yondelis (J9352) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

YONDELIS Medically Unlikely Edits (MUE)

The most billing units of J9352 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.1 mg.

Practitioner Office & Hospital Outpatient

40 units / day

= 4 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

YONDELIS Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

unresectable or metastatic liposarcoma or leiomyosarcoma

Drug Class

Alkylating Activity [MoA]Alkylating Drug [EPC]

Frequently Asked Questions

Is there an available Yondelis billing and coding guide?

Billing and coding information for YONDELIS can be found through Janssen. Visit Here →

Are there any available Yondelis patient assistance programs?

YONDELIS patient assistance information can be found through Janssen. Visit Here →

Where can I find Yondelis prescribing information?

YONDELIS prescribing information can be found at the link below: Visit Here →

Where can I find Yondelis side effect information?

Information regarding YONDELIS's side effects can be found at MedlinePlus Visit Here →

Does billing YONDELIS require JZ/JW wastage modifiers?

CMS has identified YONDELIS(J9352) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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