Home › Drug Codes › J Codes › J3101 · TNKASE
Updated July 1st, 2026

TNKASE J Code: J3101

Injection, tenecteplase, 1 mg

Login to unlock all benchmarks

Q4 2026 Medicare Payment Limit for J3101, effective October 1, 2026: $230.742 per HCPCS billing unit, up 6.1% from $217.421. From CMS's final file.

?
Medicare Payment Limit ?
$217.421
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$217.421
/ HCPCS billing unit · APC 9002
ASP ?
$•••.••
Login to view
WAC · AWP ?
$•••.••
Login to view
NDCs Crosswalked ?
3
View NDC crosswalk →

Drug & Product Overview

HCPCS Descriptor Injection, tenecteplase, 1 mg
HCPCS Added Date January 1, 2009
Manufacturer Genentech
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Kit

About TNKASE

Tnkase is a medication aligned to the HCPCS J Code: J3101 for billing, pricing, and reimbursement purposes in the United States. Classified under Cardiology, it is administered via the intravenous route and manufactured by Genentech.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
50242-0014-03 TNKase Genentech, Inc. 25 Kit
50242-0120-47 TNKase Genentech, Inc. 50 Kit
50242-0176-01 TNKase Genentech, Inc. 50 Kit
Login for the full NDC crosswalk View pricing, complete NDC-to-HCPCS alignments, and package details.
Login →

TNKASE Pricing & Reimbursement

J3101 Private Payer Reimbursement
$186.73 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

TNKASE CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96374 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug
JW / JZ modifiers apply

CMS has identified Tnkase (J3101) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

TNKASE Medically Unlikely Edits (MUE)

The most billing units of J3101 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient
50 units / day
= 50 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

TNKASE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acute Ischemic Stroke Acute ST Elevation Myocardial Infarction Acute ST Elevation Myocardial Infarction (STEMI)

Login for BuyandBill.com Analytics

Unlock deeper insights with BuyandBill’s Comparative Report!

  • Compare ASP, WAC, and AWP across drugs.
  • Visualize Drug Price Movement Over Time
  • Tailor reports to drug class, manufacturer, or HCPCS Code.
  • Compare Biosimilar and 505(b)(2) products.
Access Full Report →

Frequently Asked Questions

Is there an available Tnkase billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for TNKASE.
Are there any available Tnkase patient assistance programs?
TNKASE patient assistance information can be found through Genentech. Visit Here →
Where can I find Tnkase prescribing information?
TNKASE prescribing information can be found at the link below: Visit Here →
Where can I find Tnkase side effect information?
Our team has not yet identified a source of side effects information for TNKASE. Please check back in a few weeks.
Does billing TNKASE require JZ/JW wastage modifiers?
CMS has identified TNKASE(J3101) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.

Related Drug Codes

Explore billing, coding, and pricing for drugs related to TNKASE.

J2997ACTIVASEInjection, alteplase recombinant, 1 mgGenentechAdded January 1, 2001C9248CLEVIPREXInjection, clevidipine butyrate, 1 mgChiesi USAAdded January 1, 2009C9482SOTALOL HCLInjection, sotalol hydrochloride, 1 mgAltathera PharmaceuticalsAdded October 1, 2016J0130ABCIXIMABInjection abciximab, 10 mgAdded January 1, 1999J0153ADENOCARDInjection, adenosine, 1 mg (not to be used to report any adenosine phosphate compounds)Multiple ManufacturersAdded January 1, 2015J0162EPINEPHRINE HCLInjection, epinephrine (fresenius), not therapeutically equivalent to j0165, 0.1 mgFresenius KabiAdded January 1, 2026J0163ADRENALINInjection, epinephrine in sodium chloride (endo), 0.1 mgPar Pharmaceutical, IncAdded October 1, 2025J0164EPINEPHRINE (BAXTER)Injection, epinephrine in sodium chloride (baxter), 0.1 mgBaxter HealthcareAdded October 1, 2025J0165EPINEPHRINE HCLInjection, epinephrine, not otherwise specified, 0.1 mgMultiple ManufacturersAdded July 1, 2025J0166EPINEPHRINE HCL (BELCHER)Injection, epinephrine (bpi), not therapeutically equivalent to j0165, 0.1 mgMultiple ManufacturersAdded July 1, 2025