Home › Drug Codes › J Codes › J2327 · Skyrizi
Updated July 1st, 2026

Skyrizi J Code: J2327

Injection, risankizumab-rzaa, intravenous, 1 mg

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Q4 2026 Medicare Payment Limit for J2327, effective October 1, 2026: $14.011 per HCPCS billing unit, down 3.6% from $14.531. From CMS's final file.

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Medicare Payment Limit ?
$14.531
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$14.531
/ HCPCS billing unit · APC 9013
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Injection, risankizumab-rzaa, intravenous, 1 mg
HCPCS Added Date January 1, 2023
Manufacturer Abbvie
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Injection

About Skyrizi

Skyrizi is a medication aligned to the HCPCS J Code: J2327 for billing, pricing, and reimbursement purposes in the United States. Classified under Immunology: Anti-TNF, it is administered via the intravenous route and manufactured by Abbvie.

According to CMS Drug Use Information: This medication is used to treat plaque psoriasis and psoriatic arthritis. It is also used to treat certain bowel diseases (Crohn's disease, ulcerative colitis). Risankizumab belongs to a class of drugs known as monoclonal antibodies. It works by blocking a certain natural protein in your body (interleukin-23) that may cause inflammation and swelling.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00074-5015-01 Skyrizi AbbVie Inc. 600 600 MG / 10 ML
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Skyrizi Pricing & Reimbursement

J2327 Private Payer Reimbursement
$15.07 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Skyrizi Claims Performance

Claims from Jan 2026 – Aug 2026
Claim Denial Rate 20.78%
Avg. Days to File 7.7days
Avg. Days to Pay 25.4days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J2327 claims analytics on FocalPoint →
OnPoint Oncology

Skyrizi CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
96372 Login for More Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular Login for More
JW / JZ modifiers apply

CMS has identified Skyrizi (J2327) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

Skyrizi Medically Unlikely Edits (MUE)

The most billing units of J2327 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient
1,200 units / day
= 1,200 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

Skyrizi Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Active psoriatic arthritis Moderate-to-severe plaque psoriasis Moderately to severely active Crohn's disease Moderately to severely active ulcerative colitis
Drug Class
Interleukin-23 Antagonist [EPC]Interleukin-23 Antagonists [MoA]

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Frequently Asked Questions

Is there an available Skyrizi billing and coding guide?
Billing and coding information for Skyrizi can be found through Abbvie. Visit Here →
Are there any available Skyrizi patient assistance programs?
Skyrizi patient assistance information can be found through Abbvie. Visit Here →
Where can I find Skyrizi prescribing information?
Skyrizi prescribing information can be found at the link below: Visit Here →
Where can I find Skyrizi side effect information?
Information regarding Skyrizi's side effects can be found at MedlinePlus Visit Here →
Does billing Skyrizi require JZ/JW wastage modifiers?
CMS has identified Skyrizi(J2327) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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