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Updated July 1st, 2026

RYONCIL J Code: J3402

Injection, remestemcel-l-rknd, per therapeutic dose

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Q4 2026 Medicare Payment Limit for J3402, effective October 1, 2026: $202,159.938 per HCPCS billing unit, down 0.7% from $203,659.763. From CMS's final file.

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Medicare Payment Limit ?
$203,659.763
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$203,659.763
/ HCPCS billing unit · APC 0886
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
12
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Drug & Product Overview

HCPCS Descriptor Injection, remestemcel-l-rknd, per therapeutic dose
HCPCS Added Date October 1, 2025
Manufacturer Mesoblast
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Form Kit

About RYONCIL

Ryoncil is a medication aligned to the HCPCS J Code: J3402 for billing, pricing, and reimbursement purposes in the United States. This Misc. medication is administered via the intravenous route and manufactured by Mesoblast.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 12 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
73648-0111-01 Ryoncil Mesoblast 1 Kit
73648-0112-02 Ryoncil Mesoblast 1 Kit
73648-0113-03 Ryoncil Mesoblast 1 Kit
73648-0114-01 Ryoncil Mesoblast 1 Kit
73648-0115-02 Ryoncil Mesoblast 1 Kit
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RYONCIL
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RYONCIL Pricing & Reimbursement

J3402 Private Payer Reimbursement
$257,027.25 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

RYONCIL CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

RYONCIL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Steroid-refractory acute graft-versus-host disease

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Frequently Asked Questions

Is there an available Ryoncil billing and coding guide?
Billing and coding information for RYONCIL can be found through Mesoblast, Inc.. Visit Here →
Are there any available Ryoncil patient assistance programs?
RYONCIL patient assistance information can be found through Mesoblast, Inc.. Visit Here →
Where can I find Ryoncil prescribing information?
Ryoncil prescribing information can be found through the link below. Visit Here →
Where can I find Ryoncil side effect information?
Ryoncil side effect information can be found at the link below. Visit Here →
Does billing Ryoncil require wastage modifiers?
CMS does not include RYONCIL (J3402) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3402. For more information, visit the link below.

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