Home › Drug Codes › J Codes › J9312 · RITUXAN
Updated October 1st, 2026

RITUXAN J Code: J9312

Injection, rituximab, 10 mg

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Medicare Payment Limit ?
$72.094
down 1.6% since Q3 2026
/ HCPCS billing unitQ3 2026: $73.278
APC Payment Limit ?
$72.094
down 1.6% since Q3 2026
/ HCPCS billing unitQ3 2026: $73.278
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
2
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Drug & Product Overview

HCPCS Descriptor Injection, rituximab, 10 mg
HCPCS Added Date January 1, 2019
Manufacturer Genentech
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Injection, Solution

About RITUXAN

Rituxan is a medication aligned to the HCPCS J Code: J9312 for billing, pricing, and reimbursement purposes in the United States. This Oncology medication is administered via the intravenous route and manufactured by Genentech.

According to CMS Drug Use Information: Rituximab is used to treat certain types of cancer (such as non-Hodgkin's lymphoma, chronic lymphocytic leukemia). It works by slowing or stopping the growth of cancer cells. Some brands of rituximab are also used to treat rheumatoid arthritis and can decrease joint pain and swelling. This drug is also used to treat certain types of blood vessel disease (such as granulomatosis with polyangiitis, microscopic polyangiitis) and can decrease the swelling of the blood vessels. Rituximab is also used to treat a certain skin condition (pemphigus vulgaris). It helps to reduce the number of skin lesions. This monograph is about the following rituximab products: rituximab, rituximab-abbs, rituximab-arrx, and rituximab-pvvr.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
50242-0051-21 Rituxan Genentech, Inc. 10 100 MG / 10 ML
50242-0053-06 Rituxan Genentech, Inc. 50 500 MG / 50 ML
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RITUXAN Pricing & Reimbursement

J9312 Private Payer Reimbursement
$77.83 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q4 2026

Rituximab Biosimilar Information:

RITUXAN Approval Date: November 26, 1997

Product Name HCPCS Code Active Ingredient BLA Type
Rituxan J9312 Rituximab 351(a) Originator Product
Truxima Q5115 Rituximab 351(k) Interchangeable
Ruxience Q5119 Rituximab 351(k) Biosimilar
Riabni Q5123 Rituximab 351(k) Biosimilar
Zimrixby N/A Rituximab 351(k) Biosimilar
4 biosimilars FDA-approved since 2018 See each approval by month on the BuyandBill.com Pipeline calendar. Comes with Pro. Every rituximab approval, month by month.
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RITUXAN Claims Performance

Claims from Jan 2026 – Aug 2026
Claim Denial Rate 11.69%
Avg. Days to File 7.8days
Avg. Days to Pay 24.6days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J9312 claims analytics on FocalPoint →
OnPoint Oncology

RITUXAN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96413 Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
JW / JZ modifiers apply

CMS has identified Rituxan (J9312) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

RITUXAN Medically Unlikely Edits (MUE)

The most billing units of J9312 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 10 mg.

Practitioner Office & Hospital Outpatient
150 units / day
= 1,500 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

RITUXAN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Chronic Lymphocytic Leukemia (CLL) Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) Non-Hodgkin's Lymphoma (NHL) Non-Hodgkin's Lymphoma (NHL) — Zevalin regimen Pemphigus Vulgaris (PV) Rheumatoid Arthritis (RA)
Drug Class
CD20-directed Antibody Interactions [MoA]CD20-directed Cytolytic Antibody [EPC]

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Compare RITUXAN with its biosimilars

  • RITUXAN J9312
  • TRUXIMA Q5115
  • RUXIENCE Q5119
  • RIABNI Q5123

ASP, the Medicare payment limit, WAC and AWP for all 4 drugs on one timeline, with 10+ years of monthly history.

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Frequently Asked Questions

Is there an available Rituxan billing and coding guide?
Billing and coding information for RITUXAN can be found through Genentech. Visit Here →
Are there any available Rituxan patient assistance programs?
RITUXAN patient assistance information can be found through Genentech. Visit Here →
Where can I find Rituxan prescribing information?
RITUXAN prescribing information can be found at the link below: Visit Here →
Where can I find Rituxan side effect information?
Information regarding RITUXAN's side effects can be found at MedlinePlus Visit Here →
Does billing RITUXAN require JZ/JW wastage modifiers?
CMS has identified RITUXAN(J9312) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to RITUXAN.

Q5115TRUXIMAInjection, rituximab-abbs, biosimilar, (truxima), 10 mgTevaAdded July 1, 2019Q5119RUXIENCEInjection, rituximab-pvvr, biosimilar, (ruxience), 10 mgPfizerAdded July 1, 2020Q5123RIABNIInjection, rituximab-arrx, biosimilar, (riabni), 10 mgAmgenAdded July 1, 2021J9301GAZYVAInjection, obinutuzumab, 10 mgGenentechAdded January 1, 2015J2329BRIUMVIInjection, ublituximab-xiiy, 1mgTG TherapeuticsAdded July 1, 2023C9142AlymsysInjection, bevacizumab-maly, biosimilar, (alymsys), 10 mgAmneal PharmaceuticalsAdded October 1, 2022C9146ELAHEREInjection, mirvetuximab soravtansine-gynx, 1 mgAbbVieAdded April 1, 2023C9147IMJUDOInjection, tremelimumab-actl, 1 mgAstraZenecaAdded April 1, 2023C9148TECVAYLIInjection, teclistamab-cqyv, 0.5 mgJanssenAdded April 1, 2023C9155EPKINLYInjection, epcoritamab-bysp, 0.16 mgGenmabAdded October 1, 2023

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