BRIUMVI J Code: J2329

Drug & Product Overview

HCPCS Descriptor Injection, ublituximab-xiiy, 1mg

HCPCS Added Date July 1, 2023

Manufacturer TG Therapeutics

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Solution, Concentrate

About BRIUMVI

Briumvi is a medication aligned to the HCPCS J Code: J2329 for billing, pricing, and reimbursement purposes in the United States. It is a Neurology drug administered via the intravenous route and manufactured by TG Therapeutics.

According to CMS Drug Use Information: This medication is used to treat multiple sclerosis (MS). Ublituximab is not a cure for MS but it is thought to help by preventing immune system cells (lymphocytes) from attacking the nerves in your brain and spinal cord. Ublituximab belongs to a class of drugs known as monoclonal antibodies. It helps decrease the number of episodes of disease worsening (relapses) and may prevent or delay disability.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
73150-0150-06	Briumvi	TG Therapeutics, Inc.	150	150 MG / 6 ML

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BRIUMVI Pricing & Reimbursement

J2329 Private Payer Reimbursement

$70.57 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

BRIUMVI Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 18.07%

Avg. Days to File 8.6days

Avg. Days to Pay 24.4days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J2329 claims analytics on FocalPoint →

BRIUMVI CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Briumvi (J2329) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

BRIUMVI Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

relapsing forms of multiple sclerosis (clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease)

Drug Class

CD20-directed Antibody Interactions [MoA]CD20-directed Cytolytic Antibody [EPC]

Frequently Asked Questions

Is there an available Briumvi billing and coding guide?

Billing and coding information for BRIUMVI can be found through TG THERAPEUTICS, INC.. Visit Here →

Are there any available Briumvi patient assistance programs?

BRIUMVI patient assistance information can be found through TG THERAPEUTICS, INC.. Visit Here →

Where can I find Briumvi prescribing information?

BRIUMVI prescribing information can be found at the link below: Visit Here →

Where can I find Briumvi side effect information?

Information regarding BRIUMVI's side effects can be found at MedlinePlus Visit Here →

Does billing BRIUMVI require JZ/JW wastage modifiers?

CMS has identified BRIUMVI(J2329) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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