PHENYTOIN SODIUM J Code: J1165

Drug & Product Overview

HCPCS Descriptor Injection, phenytoin sodium, per 50 mg

HCPCS Added Date January 1, 1982

Manufacturer Multiple Manufacturers

Route of Administration Intramuscular, Intravenous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection

About PHENYTOIN SODIUM

Phenytoin Sodium is a medication aligned to the HCPCS J Code: J1165 for billing, pricing, and reimbursement purposes in the United States. It is a Neurology drug administered via the intramuscular or intravenous routes and manufactured by multiple companies.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 11 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00641-0493-25	Phenytoin Sodium	Hikma Pharmaceuticals USA Inc.	50	100 MG / 2 ML
00641-2555-10	Phenytoin Sodium	Hikma Pharmaceuticals USA Inc.	50	250 MG / 5 ML
00641-2555-45	Phenytoin Sodium	Hikma Pharmaceuticals USA Inc.	125	250 MG / 5 ML
00641-6138-25	Phenytoin Sodium	Hikma Pharmaceuticals USA Inc.	50	100 MG / 2 ML
00641-6139-10	Phenytoin Sodium	Hikma Pharmaceuticals USA Inc.	50	250 MG / 5 ML
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PHENYTOIN SODIUM Pricing & Reimbursement

J1165 Private Payer Reimbursement

$0.77 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

PHENYTOIN SODIUM CPT Administration Codes

CPT Code	Description
96374	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug

JW / JZ modifiers apply

CMS has identified Phenytoin Sodium (J1165) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

PHENYTOIN SODIUM Medically Unlikely Edits (MUE)

The most billing units of J1165 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 50 mg.

Practitioner Office & Hospital Outpatient

50 units / day

= 2,500 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

PHENYTOIN SODIUM Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Generalized tonic-clonic status epilepticus Parenteral substitution for oral phenytoin therapy Prevention and treatment of seizures occurring during neurosurgery Seizures occurring during neurosurgery Status Epilepticus Substitution for oral phenytoin (short-term)

Drug Class

Anti-epileptic Agent [EPC]Cytochrome P450 1A2 Inducers [MoA]Cytochrome P450 2B6 Inducers [MoA]Cytochrome P450 2C19 Inducers [MoA]Cytochrome P450 2C8 Inducers [MoA]Cytochrome P450 2C9 Inducers [MoA]Cytochrome P450 2D6 Inducers [MoA]Cytochrome P450 3A Inducers [MoA]Decreased Central Nervous System Disorganized Electrical Activity [PE]

Frequently Asked Questions

Is there an available Phenytoin Sodium billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for PHENYTOIN SODIUM.

Are there any available Phenytoin Sodium patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for PHENYTOIN SODIUM.

Where can I find Phenytoin Sodium prescribing information?

Our team is still working to identify a prescribing information source for PHENYTOIN SODIUM

Where can I find Phenytoin Sodium side effect information?

Our team has not yet identified a source of side effects information for PHENYTOIN SODIUM. Please check back in a few weeks.

Does billing PHENYTOIN SODIUM require JZ/JW wastage modifiers?

CMS has identified PHENYTOIN SODIUM(J1165) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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