Numbrino C Code: C9143

Drug & Product Overview

HCPCS Descriptor Cocaine hydrochloride nasal solution (numbrino), 1 mg

HCPCS Added Date January 1, 2023

Manufacturer Omnivium Pharmaceuticals

Route of Administration Topical

Generic Status Single-Source; Branded

Dosage Form Solution

About Numbrino

Numbrino is a medication aligned to the HCPCS C Code: C9143 for billing, pricing, and reimbursement purposes in the United States. It is an Anesthetic drug administered via the topical route and manufactured by Omnivium Pharmaceuticals.

Manufacturers, reach out to us to add more information.

NDC Code Information

1 NDC package is crosswalked to C9143. Package detail is available to logged-in subscribers.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
•••••-••••-•• Log in to view	Numbrino

Login to view 1 NDC package View pricing, complete NDC-to-HCPCS alignments, and package details.

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Numbrino Pricing & Reimbursement

C9143 Private Payer Reimbursement

$2.28 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Cocaine Hydrochloride Nasal 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
C9143	Omnivium Pharmaceuticals	Cocaine Hydrochloride Nasal	Cocaine hydrochloride nasal solution (numbrino), 1 mg

Numbrino Medically Unlikely Edits (MUE)

The most billing units of C9143 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

160 units / day

= 160 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

Not on the CMS JW / JZ list

CMS does not include Numbrino (C9143) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing C9143. Wastage billing guide →

Numbrino Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Local anesthesia of the nasal mucous membranes for diagnostic procedures and surgeries

Frequently Asked Questions

Is there an available Numbrino billing and coding guide?

We have not yet identified a manufacturer source of Numbrino billing and coding information.

Are there any available Numbrino patient assistance programs?

Our team did not identify a source for Numbrino patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Numbrino prescribing information?

Numbrino prescribing information can be found at the link below: Visit Here →

Where can I find Numbrino side effect information?

Our team has not yet identified a source of side effects information for Numbrino. Please check back in a few weeks.

Does billing Numbrino require JZ/JW wastage modifiers?

CMS does not include Numbrino (C9143) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing C9143. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.