MITOMYCIN J Code: J9280

Drug & Product Overview

HCPCS Descriptor Injection, mitomycin, 5 mg

HCPCS Added Date January 1, 1986

Manufacturer Multiple Manufacturers

Route of Administration Intravenous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution | Not Available

About MITOMYCIN

Mitomycin is a medication aligned to the HCPCS J Code: J9280 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: Mitomycin is used to treat various types of cancer (such as stomach/pancreas cancer). It works by slowing or stopping the growth of cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 30 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00143-9135-01	Mitomycin	Hikma Pharmaceuticals USA Inc.	4	20 MG
16729-0115-05	Mitomycin	Accord Healthcare, Inc.	1	5 MG / 10 ML
25021-0250-20	Mitomycin	Sagent Pharmaceuticals	1	5 MG / 10 ML
55150-0450-01	Mitomycin	Eugia Us Llc	1	5 MG / 10 ML
65219-0564-20	Mitomycin	Fresenius Kabi USA, LLC	1	5 MG / 10 ML
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MITOMYCIN Pricing & Reimbursement

J9280 Private Payer Reimbursement

$26.86 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

MITOMYCIN CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

CMS does not include Mitomycin (J9280) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9280. Wastage billing guide →

MITOMYCIN Medically Unlikely Edits (MUE)

The most billing units of J9280 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 5 mg.

Practitioner Office & Hospital Outpatient

12 units / day

= 60 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

MITOMYCIN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

disseminated adenocarcinoma of the stomach or pancreas

Drug Class

Alkylating Activity [MoA]Alkylating Drug [EPC]

Frequently Asked Questions

Is there an available Mitomycin billing and coding guide?

We have not yet identified a manufacturer source of Mitomycin billing and coding information.

Are there any available Mitomycin patient assistance programs?

Our team did not identify a source for Mitomycin patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Mitomycin prescribing information?

MITOMYCIN prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Mitomycin side effect information?

Our team has not yet identified a source of side effects information for MITOMYCIN. Please check back in a few weeks.

Does billing MITOMYCIN require JZ/JW wastage modifiers?

CMS does not include MITOMYCIN (J9280) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9280. For more information, visit the link below.

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