METHOTREXATE J Code: J9255

Drug & Product Overview

HCPCS Descriptor Injection, methotrexate (accord), not therapeutically equivalent to j9260, 50 mg

HCPCS Added Date January 1, 2024

Manufacturer ACCORD HEALTHCARE

Generic Status Single-Source; Branded

About METHOTREXATE

Methotrexate is a medication aligned to the HCPCS J Code: J9255 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug manufactured by ACCORD HEALTHCARE.

Manufacturers, reach out to us to add more information.

NDC Code Information

No NDC packages are aligned to J9255 in publicly available CMS files.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
No public NDC alignments

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METHOTREXATE Pricing & Reimbursement

J9255 Private Payer Reimbursement

$5.95 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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METHOTREXATE CPT Administration Codes

CPT Code	Description
96409	Chemotherapy administration; intravenous, push technique, single or initial substance/drug
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Login for More	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure) Login for More

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

METHOTREXATE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acute Lymphoblastic Leukemia Meningeal Leukemia: Prophylaxis and Treatment Non-Hodgkin Lymphoma Osteosarcoma Breast Cancer Squamous Cell Carcinoma of the Head and Neck Gestational Trophoblastic Neoplasia Rheumatoid Arthritis Polyarticular Juvenile Idiopathic Arthritis Psoriasis

Frequently Asked Questions

Is there an available Methotrexate billing and coding guide?

We have not yet identified a manufacturer source of Methotrexate billing and coding information.

Are there any available Methotrexate patient assistance programs?

Our team did not identify a source for Methotrexate patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Methotrexate prescribing information?

METHOTREXATE prescribing information can be found at the link below: Visit Here →

Where can I find Methotrexate side effect information?

Information regarding METHOTREXATE's side effects can be found at MedlinePlus Visit Here →

Does billing METHOTREXATE require JZ/JW wastage modifiers?

CMS does not include METHOTREXATE (J9255) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9255. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.