MESNA J Code: J9209

Drug & Product Overview

HCPCS Descriptor Injection, mesna, 200 mg

HCPCS Added Date January 1, 1990

Manufacturer Multiple Manufacturers

Route of Administration Intravenous

Generic Status Multi-Source; Generic

Dosage Type Multi-Dose

Dosage Form Injection, Solution | Not Available

About MESNA

Mesna is a medication aligned to the HCPCS J Code: J9209 for billing, pricing, and reimbursement purposes in the United States. Classified under Oncology, it is administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used to reduce the risk of bleeding in the bladder (hemorrhagic cystitis), which is a very serious side effect of treatment with a cancer chemotherapy drug called ifosfamide. Mesna helps to protect the lining of the bladder against damage from ifosfamide. The body breaks down ifosfamide to form a product that can harm the bladder, and mesna works by making this product less harmful. However, mesna does not change ifosfamide's anti-cancer effects.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 8 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00143-9260-01	mesna	Hikma Pharmaceuticals USA Inc.	5	1000 MG / 10 ML
00338-1305-01	Mesnex	Baxter Healthcare Company	5	1000 MG / 10 ML
25021-0201-10	Mesna	Sagent Pharmaceuticals	5	1000 MG / 10 ML
63323-0733-11	Mesna	Fresenius Kabi USA, LLC	5	1000 MG / 10 ML
70860-0209-10	Mesna	Athenex Pharmaceutical Division, LLC	5	100 MG
•••••-••••-•• Log in to view	MESNA
	MESNA
	MESNA

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MESNA Pricing & Reimbursement

J9209 Private Payer Reimbursement

$1.63 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

MESNA Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 10.5%

Avg. Days to File 24.9days

Avg. Days to Pay 29.2days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J9209 claims analytics on FocalPoint →

MESNA CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

CMS does not include Mesna (J9209) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9209. Wastage billing guide →

MESNA Medically Unlikely Edits (MUE)

The most billing units of J9209 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 200 mg.

Practitioner Office & Hospital Outpatient

55 units / day

= 11,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

MESNA Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

ifosfamide-induced hemorrhagic cystitis

Drug Class

Cytoprotective Agent [EPC]

Frequently Asked Questions

Is there an available Mesna billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for MESNA.

Are there any available Mesna patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for MESNA.

Where can I find Mesna prescribing information?

MESNA prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Mesna side effect information?

Our team has not yet identified a source of side effects information for MESNA. Please check back in a few weeks.

Does billing MESNA require JZ/JW wastage modifiers?

CMS does not include MESNA (J9209) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9209. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.