LABETALOL HCL J Code: J1921

Drug & Product Overview

HCPCS Descriptor Injection, labetalol hydrochloride (hikma), not therapeutically equivalent to j1920, 5 mg

HCPCS Added Date July 1, 2023

Manufacturer Hikma

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Multi-Dose

Dosage Form Injection | Injection, Solution

About LABETALOL HCL

Labetalol HCL is a medication aligned to the HCPCS J Code: J1921 for billing, pricing, and reimbursement purposes in the United States. It is a Cardiology drug administered via the intravenous route and manufactured by Hikma.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. Showing 2 of 4 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00143-9183-10	Labetalol Hydrochloride	Hikma Pharmaceuticals USA Inc.	40	20 MG / 4 ML
00641-6252-10	Labetalol HCl	Hikma Pharmaceuticals USA Inc.	20	10 MG / 2 ML
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	LABETALOL HCL

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LABETALOL HCL Pricing & Reimbursement

J1921 Private Payer Reimbursement

$1.15 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

Labetalol Hydrochloride 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J1920	Generic Code (Multiple Manufacturers)	Labetalol Hydrochloride	Injection, labetalol hydrochloride, 5 mg
J1921	Hikma	Labetalol Hydrochloride	Injection, labetalol hydrochloride (hikma), not therapeutically equivalent to j1920, 5 mg

LABETALOL HCL CPT Administration Codes

CPT Code	Description
96374	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug

JW / JZ modifiers apply

CMS has identified Labetalol HCL (J1921) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

LABETALOL HCL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Severe Hypertension

Drug Class

Adrenergic beta-Antagonists [MoA]beta-Adrenergic Blocker [EPC]

Frequently Asked Questions

Is there an available Labetalol Hcl billing and coding guide?

We have not yet identified a manufacturer source of Labetalol Hcl billing and coding information.

Are there any available Labetalol Hcl patient assistance programs?

Our team did not identify a source for Labetalol Hcl patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Labetalol Hcl prescribing information?

LABETALOL HCL prescribing information can be found at the link below: Visit Here →

Where can I find Labetalol Hcl side effect information?

Information regarding LABETALOL HCL's side effects can be found at MedlinePlus Visit Here →

Does billing LABETALOL HCL require JZ/JW wastage modifiers?

CMS has identified LABETALOL HCL(J1921) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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