IXINITY J Code: J7213

Drug & Product Overview

HCPCS Descriptor Injection, coagulation factor ix (recombinant), ixinity, 1 i.u.

HCPCS Added Date July 1, 2023

Manufacturer Aptevo BioTherapeutics

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Kit | Not Available

About IXINITY

Ixinity is a medication aligned to the HCPCS J Code: J7213 for billing, pricing, and reimbursement purposes in the United States. It is a Hematology drug administered via the intravenous route and manufactured by Aptevo BioTherapeutics.

According to CMS Drug Use Information: This medication is used to prevent or control bleeding in people with little or no factor IX (due to hemophilia B, Christmas disease). Factor IX is a protein (clotting factor) in the blood that works with other clotting factors to help the blood clot and stop bleeding. People with little or no factor IX are at risk for bleeding longer after an injury/surgery or bleeding suddenly (often in the joints/muscle) without an obvious cause. This medication should not be used to treat other types of factor deficiencies (such as factors II, VII, VIII, X) or factor problems (such as inhibitor to factor XIII), to reverse the effects of "blood thinners" (such as warfarin), or to treat bleeding from low levels of liver-dependent clotting factors (due to liver problems).

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 4 of 10 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
59137-0282-05	Ixinity	Medexus Pharma, Inc.	1	Kit
59137-0283-05	Ixinity	Medexus Pharma, Inc.	1	Kit
59137-0284-05	Ixinity	Medexus Pharma, Inc.	1	Kit
59137-0289-05	Ixinity	Medexus Pharma, Inc.	1	Kit
•••••-••••-•• Log in to view	IXINITY
	IXINITY
	IXINITY

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IXINITY Pricing & Reimbursement

J7213 Private Payer Reimbursement

$2.05 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

Coagulation Factor Ix 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J7213	Generic Code (Multiple Manufacturers)	Coagulation Factor Ix	Injection, coagulation factor ix (recombinant), ixinity, 1 i.u.

IXINITY CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Ixinity (J7213) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

IXINITY Medically Unlikely Edits (MUE)

The most billing units of J7213 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 iu.

Practitioner Office & Hospital Outpatient

12,000 units / day

= 12,000 iu per day

MAI 1 · Line Edit. Per-line limit: units are checked per claim line; medically necessary units beyond the limit may be billable on separate lines with appropriate modifiers. See all MUE limits →

IXINITY Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Hemophilia B

Frequently Asked Questions

Is there an available Ixinity billing and coding guide?

We have not yet identified a manufacturer source of Ixinity billing and coding information.

Are there any available Ixinity patient assistance programs?

IXINITY patient assistance information can be found through Aptevo Biotherapeutics, Llc. Visit Here →

Where can I find Ixinity prescribing information?

IXINITY prescribing information can be found at the link below: Visit Here →

Where can I find Ixinity side effect information?

Our team has not yet identified a source of side effects information for IXINITY. Please check back in a few weeks.

Does billing IXINITY require JZ/JW wastage modifiers?

CMS has identified IXINITY(J7213) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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