Home › Drug Codes › J Codes › J0168 · EPINEPHRINE HCL
Updated July 1st, 2026

EPINEPHRINE HCL J Code: J0168

Injection, epinephrine (international medication systems), not therapeutically equivalent to j0165, 0.1 mg

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Q4 2026 Medicare Payment Limit for J0168, effective October 1, 2026: $2.697 per HCPCS billing unit, up 5.6% from $2.555. From CMS's final file.

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Medicare Payment Limit ?
$2.555
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
2
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Drug & Product Overview

HCPCS Descriptor Injection, epinephrine (international medication systems), not therapeutically equivalent to j0165, 0.1 mg
HCPCS Added Date July 1, 2025
Manufacturer A-S Medication Solutions
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Form Injection

About EPINEPHRINE HCL

Epinephrine HCL is a medication aligned to the HCPCS J Code: J0168 for billing, pricing, and reimbursement purposes in the United States. This Cardiology medication is administered via the intravenous route and manufactured by A-S Medication Solutions.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. Showing 1 of 2 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
50090-7037-00 Epinephrine A-S Medication Solutions 1 0.1 MG / 1 ML
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EPINEPHRINE HCL Pricing & Reimbursement

J0168 Private Payer Reimbursement
$2.91 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Epinephrine 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J0162 Fresenius Kabi Epinephrine Injection, epinephrine (fresenius), not therapeutically equivalent to j0165, 0.1 mg
J0163 Par Pharmaceutical, Inc Epinephrine Injection, epinephrine in sodium chloride (endo), 0.1 mg
J0164 Baxter Healthcare Epinephrine Injection, epinephrine in sodium chloride (baxter), 0.1 mg
J0165 Generic Code (Multiple Manufacturers) Epinephrine Injection, epinephrine, not otherwise specified, 0.1 mg
J0166 Generic Code (Multiple Manufacturers) Epinephrine Injection, epinephrine (bpi), not therapeutically equivalent to j0165, 0.1 mg
J0167 Log in to view
J0168 Generic Code (Multiple Manufacturers) Epinephrine Injection, epinephrine (international medication systems), not therapeutically equivalent to j0165, 0.1 mg
J0169 Log in to view
Log in to view all 8 505(b)(2) codes

EPINEPHRINE HCL CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96374 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug
96375 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); each additional sequential intravenous push of a new substance/drug.
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

EPINEPHRINE HCL Medically Unlikely Edits (MUE)

The most billing units of J0168 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.1 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office
20 units / day
= 2 mg per day
Hospital Outpatient
120 units / day
= 12 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

EPINEPHRINE HCL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Hypotension associated with Septic Shock
Drug Class
Adrenergic alpha-Agonists [MoA]Adrenergic beta-Agonists [MoA]Catecholamine [EPC]Catecholamines [CS]alpha-Adrenergic Agonist [EPC]beta-Adrenergic Agonist [EPC]

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Frequently Asked Questions

Is there an available EPINEPHRINE HCL billing and coding guide?
Our team has not identified a manufacturer-source of billing and coding information for EPINEPHRINE HCL. Please reach out to our team if this is a mistake.
Are there any available EPINEPHRINE HCL patient assistance programs?
Our team has not identified a source of patient assistance information for EPINEPHRINE HCL. Please reach out to us if this is a mistake.
Where can I find EPINEPHRINE HCL prescribing information?
EPINEPHRINE HCL prescribing information can be found at the link below. Visit Here →
Where can I find EPINEPHRINE HCL side effect information?
Side effect information for EPINEPHRINE HCL can be found through MedlinePlus. Visit Here →
Does billing EPINEPHRINE HCL require JZ/JW wastage modifiers?
CMS does not include EPINEPHRINE HCL (J0168) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0168. For more information, visit the link below.

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to EPINEPHRINE HCL.

J0162EPINEPHRINE HCLInjection, epinephrine (fresenius), not therapeutically equivalent to j0165, 0.1 mgFresenius KabiAdded January 1, 2026J0164EPINEPHRINE (BAXTER)Injection, epinephrine in sodium chloride (baxter), 0.1 mgBaxter HealthcareAdded October 1, 2025J0165EPINEPHRINE HCLInjection, epinephrine, not otherwise specified, 0.1 mgMultiple ManufacturersAdded July 1, 2025J0166EPINEPHRINE HCL (BELCHER)Injection, epinephrine (bpi), not therapeutically equivalent to j0165, 0.1 mgMultiple ManufacturersAdded July 1, 2025J0169ADRENALINInjection, epinephrine (adrenalin), not therapeutically equivalent to j0165, 0.1 mgMultiple ManufacturersAdded July 1, 2025J0171ADRENALINInjection, adrenalin, epinephrine, 0.1 mgMultiple ManufacturersAdded January 1, 2011J0167EPINEPHRINE HCLInjection, epinephrine (hospira), not therapeutically equivalent to j0165, 0.1 mgMultiple ManufacturersAdded July 1, 2025J0163ADRENALINInjection, epinephrine in sodium chloride (endo), 0.1 mgPar Pharmaceutical, IncAdded October 1, 2025C9248CLEVIPREXInjection, clevidipine butyrate, 1 mgChiesi USAAdded January 1, 2009C9482SOTALOL HCLInjection, sotalol hydrochloride, 1 mgAltathera PharmaceuticalsAdded October 1, 2016