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Updated July 1st, 2026

CYCLOSPORINE J Code: J7515

Cyclosporine, oral, 25 mg

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Q4 2026 Medicare Payment Limit for J7515, effective October 1, 2026: $0.576 per HCPCS billing unit, up 4.3% from $0.552. From CMS's final file.

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Medicare Payment Limit ?
$0.552
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
11
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Drug & Product Overview

HCPCS Descriptor Cyclosporine, oral, 25 mg
HCPCS Added Date January 1, 2000
Manufacturer Multiple Manufacturers
Route of Administration Oral
Generic Status Multi-Source; Generic
Dosage Form Capsule | Capsule, Gelatin Coated | Capsule, Liquid Filled

About CYCLOSPORINE

Cyclosporine is a medication aligned to the HCPCS J Code: J7515 for billing, pricing, and reimbursement purposes in the United States. This Immunosuppressant medication is administered via the oral route and manufactured by multiple companies.

According to CMS Drug Use Information: Cyclosporine is used to prevent organ rejection in people who have received a liver, kidney, or heart transplant. It is usually taken along with other medications to allow your new organ to function normally. Cyclosporine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new organ as if it were your own.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 11 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00074-3108-32 Gengraf AbbVie Inc. 30 25 MG
00078-0240-15 Sandimmune Novartis Pharmaceuticals Corporation 30 25 MG
00093-9018-65 Cyclosporine Modified Teva Pharmaceuticals USA, Inc. 30 25 MG
23155-0837-30 Cyclosporine Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. 30 25 MG
60505-0133-00 Cyclosporine Apotex Corp. 30 25 MG
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CYCLOSPORINE Pricing & Reimbursement

J7515 Private Payer Reimbursement
$0.97 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

CYCLOSPORINE Medically Unlikely Edits (MUE)

The most billing units of J7515 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 25 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office
0 units / day
Not payable in this setting
Hospital Outpatient
90 units / day
= 2,250 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.
Not on the CMS JW / JZ list

CMS does not include Cyclosporine (J7515) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7515. Wastage billing guide →

CYCLOSPORINE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Chronic rejection in patients previously treated with other immunosuppressive agents Heart transplantation Kidney transplantation Kidney, Liver, and Heart Transplantation Kidney, liver, and heart transplantation Liver transplantation Plaque psoriasis Prophylaxis of organ rejection in kidney, liver, and heart allogeneic transplants Psoriasis Rheumatoid Arthritis Rheumatoid arthritis Treatment of chronic rejection in patients previously treated with other immunosuppressive agents
Drug Class
Calcineurin Inhibitor Immunosuppressant [EPC]Calcineurin Inhibitors [MoA]Cytochrome P450 3A4 Inhibitors [MoA]P-Glycoprotein Inhibitors [MoA]

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Frequently Asked Questions

Is there an available Cyclosporine billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for CYCLOSPORINE.
Are there any available Cyclosporine patient assistance programs?
Our team has not identified a manufacturer-published source of patient assistance information for CYCLOSPORINE.
Where can I find Cyclosporine prescribing information?
CYCLOSPORINE prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Cyclosporine side effect information?
Our team has not yet identified a source of side effects information for CYCLOSPORINE. Please check back in a few weeks.
Does billing CYCLOSPORINE require JZ/JW wastage modifiers?
CMS does not include CYCLOSPORINE (J7515) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7515. For more information, visit the link below.

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