Home › Drug Codes › J Codes › J9075 · CYCLOPHOSPHAMIDE
Updated July 1st, 2026

CYCLOPHOSPHAMIDE J Code: J9075

Injection, cyclophosphamide, not otherwise specified, 5 mg

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Q4 2026 Medicare Payment Limit for J9075, effective October 1, 2026: $0.692 per HCPCS billing unit, up 20.3% from $0.575. From CMS's final file.

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Medicare Payment Limit ?
$0.575
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$0.575
/ HCPCS billing unit · APC 0743
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
44
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Drug & Product Overview

HCPCS Descriptor Injection, cyclophosphamide, not otherwise specified, 5 mg
HCPCS Added Date April 1, 2024
Manufacturer Multiple Manufacturers
Route of Administration Intravenous, Oral
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injection, Powder, For Solution | Injection, Powder, Lyophilized, For Solution | Not Available

About CYCLOPHOSPHAMIDE

Cyclophosphamide is a medication aligned to the HCPCS J Code: J9075 for billing, pricing, and reimbursement purposes in the United States. This Oncology medication is administered via the intravenous or oral routes and manufactured by multiple companies.

According to CMS Drug Use Information: Cyclophosphamide is used to treat various types of cancer. It is a chemotherapy drug that works by slowing or stopping cell growth. Cyclophosphamide also works by decreasing your immune system's response to various diseases. It is used to treat a certain type of kidney disease in children after other treatments have not worked.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 44 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00781-3233-94 Cyclophosphamide Sandoz Inc. 100 500 MG / 25 ML
10019-0938-01 Cyclophosphamide Baxter Healthcare Company 100 500 MG / 25 ML
16714-0857-01 Cyclophosphamide NorthStar Rx LLC 200 1000 MG / 50 ML
25021-0247-50 Cyclophosphamide Sagent Pharmaceuticals 100 500 MG / 25 ML
39822-0250-01 Cyclophosphamide XGen Pharmaceuticals DJB, Inc. 100 500 MG / 25 ML
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CYCLOPHOSPHAMIDE Pricing & Reimbursement

J9075 Private Payer Reimbursement
$0.74 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Cyclophosphamide 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J9071 Eugia US Cyclophosphamide Injection, cyclophosphamide (auromedics), 5 mg
J9072 Avyxa Pharma Cyclophosphamide Injection, cyclophosphamide (frindovyx), 5 mg
J9073 Generic Code (Multiple Manufacturers) Cyclophosphamide Injection, cyclophosphamide (dr. reddy's), 5 mg
J9074 Sandoz Cyclophosphamide Injection, cyclophosphamide (sandoz), 5 mg
J9075 Generic Code (Multiple Manufacturers) Cyclophosphamide Injection, cyclophosphamide, not otherwise specified, 5 mg
J9076 Log in to view
Log in to view all 6 505(b)(2) codes

CYCLOPHOSPHAMIDE CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96413 Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

CYCLOPHOSPHAMIDE Medically Unlikely Edits (MUE)

The most billing units of J9075 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 5 mg.

Practitioner Office & Hospital Outpatient
1,500 units / day
= 7,500 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

CYCLOPHOSPHAMIDE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Malignant Diseases Malignant Diseases (malignant lymphomas, Hodgkin's disease, multiple myeloma, leukemias, mycosis fungoides, neuroblastoma, adenocarcinoma of the ovary, retinoblastoma, carcinoma of the breast) Malignant lymphomas (Stages III and IV Ann Arbor), Hodgkin's disease, lymphocytic lymphoma, mixed-cell type lymphoma, histiocytic lymphoma, Burkitt's lymphoma; multiple myeloma; leukemias (chronic lymphocytic leukemia, chronic granulocytic leukemia, acute myelogenous and monocytic leukemia, acute lymphoblastic (stem-cell) leukemia); mycosis fungoides; neuroblastoma; adenocarcinoma of the ovary; retinoblastoma; carcinoma of the breast Malignant lymphomas, multiple myeloma, leukemias, mycosis fungoides, neuroblastoma, adenocarcinoma of the ovary, retinoblastoma, carcinoma of the breast Minimal Change Nephrotic Syndrome Minimal change nephrotic syndrome

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Frequently Asked Questions

Is a Cyclophosphamide billing and coding guide available?
We have not yet identified a manufacturer source of billing and coding information for Cyclophosphamide
Is Cyclophosphamide patient assistance information available?
Our team did not identify a source for Cyclophosphamide patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Cyclophosphamide prescribing information?
Our team is still working to identify a source of prescribing information for CYCLOPHOSPHAMIDE
Where can I find Cyclophosphamide side effect information?
Information regarding CYCLOPHOSPHAMIDE's potential side effects can be found at MedlinePlus
Does billing CYCLOPHOSPHAMIDE require JZ/JW wastage modifiers?
CMS does not include CYCLOPHOSPHAMIDE (J9075) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9075. For more information, visit the link below.

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