CYANOCOBALAMIN J Code: J3420
Injection, vitamin b-12 cyanocobalamin, up to 1000 mcg
Q4 2026 Medicare Payment Limit for J3420, effective October 1, 2026: $0.648 per HCPCS billing unit, down 5.1% from $0.683. From CMS's final file.
Drug & Product Overview
About CYANOCOBALAMIN
Cyanocobalamin is a medication aligned to the HCPCS J Code: J3420 for billing, pricing, and reimbursement purposes in the United States. This Misc. medication is administered via the intramuscular or subcutaneous routes and manufactured by multiple companies.
According to CMS Drug Use Information: Cyanocobalamin is a man-made form of vitamin B12 used to treat low levels (deficiency) of this vitamin. Vitamin B12 helps your body use fat and carbohydrates for energy and make new protein. It is also important for normal blood, cells, and nerves. Most people get enough vitamin B12 in their diet, but a deficiency may occur in certain health conditions (such as poor nutrition, stomach/intestinal problems, infection, cancer). Serious vitamin B12 deficiency may result in anemia, stomach problems, and nerve damage.
Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.
NDC Code Information
Based on publicly available CMS files. Showing 5 of 47 NDCs — log in for the full crosswalk.
| NDC Code | Drug | Manufacturer | Billing Units / Pkg | Package Size |
|---|---|---|---|---|
| 00143-9619-01 | Cyanocobalamin | Hikma Pharmaceuticals USA Inc. | 30 | 30000 MCG / 30 ML |
| 00517-0031-25 | Cyanocobalamin | American Regent, Inc. | 25 | 1000 MCG / 1 ML |
| 16714-0302-10 | Cyanocobalamin | Northstar RxLLC | 100 | 1000 MCG |
| 25021-0502-01 | Cyanocobalamin | Sagent Pharmaceuticals | 25 | 1000 MCG / 1 ML |
| 50090-2709-00 | Cyanocobalamin | A-S Medication Solutions | 25 | 1000 MCG |
| •••••-••••-•• Log in to view | CYANOCOBALAMIN | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
| •••••-••••-•• Log in to view | CYANOCOBALAMIN | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
| •••••-••••-•• Log in to view | CYANOCOBALAMIN | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
CYANOCOBALAMIN Pricing & Reimbursement
National median reimbursement across major commercial payers.
Create an account on PayerPrice for more information →
Historical Graphing and Billing Calculator
Log in to calculate billing and reimbursement with live ASP, WAC & AWP pricing.
Login to use the calculator →CYANOCOBALAMIN CPT Administration Codes
The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.
| CPT Code | Description |
|---|---|
| 96372 | Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular |
CMS does not include Cyanocobalamin (J3420) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3420. Wastage billing guide →
CYANOCOBALAMIN Medically Unlikely Edits (MUE)
The most billing units of J3420 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1000 mcg.
MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →
CYANOCOBALAMIN Clinical Information
Indications and drug classification.
This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.
Login for BuyandBill.com Analytics
Unlock deeper insights with BuyandBill’s Comparative Report!
- Compare ASP, WAC, and AWP across drugs.
- Visualize Drug Price Movement Over Time
- Tailor reports to drug class, manufacturer, or HCPCS Code.
- Compare Biosimilar and 505(b)(2) products.
Frequently Asked Questions
Is there an available Cyanocobalamin billing and coding guide?
Are there any available Cyanocobalamin patient assistance programs?
Where can I find Cyanocobalamin prescribing information?
Where can I find Cyanocobalamin side effect information?
Does billing CYANOCOBALAMIN require JZ/JW wastage modifiers?
About BuyandBill.com:
The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.
Related Drug Codes
Explore billing, coding, and pricing for drugs related to CYANOCOBALAMIN.
