COSMEGEN J Code: J9120

Drug & Product Overview

HCPCS Descriptor Injection, dactinomycin, 0.5 mg

HCPCS Added Date January 1, 1984

Manufacturer Multiple Manufacturers

Route of Administration Intravenous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution | Not Available

About COSMEGEN

Cosmegen is a medication aligned to the HCPCS J Code: J9120 for billing, pricing, and reimbursement purposes in the United States. This Oncology medication is administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: Dactinomycin is used to treat cancer. It works by slowing or stopping the growth of cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 9 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
39822-2100-02	dactinomycin	XGen Pharmaceuticals DJB, Inc.	1	0.5 MG / 1 ML
42658-0008-01	Dactinomycin	Hisun Pharmaceuticals USA, Inc.	1	.5 MG
55150-0431-01	Dactinomycin	Eugia Us Llc	1	0.5 MG / 1 ML
67457-0513-05	Dactinomycin	Mylan Institutional Inc.	1	0.5 MG
71288-0129-02	Dactinomycin	Meitheal Pharmaceuticals Inc.	1	0.5 MG / 1 ML
•••••-••••-•• Log in to view	COSMEGEN
	COSMEGEN
	COSMEGEN

Login to view 4 more NDC packages View pricing, complete NDC-to-HCPCS alignments, and package details.

Login →

COSMEGEN Pricing & Reimbursement

J9120 Private Payer Reimbursement

$325.17 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

COSMEGEN CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Cosmegen (J9120) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

COSMEGEN Medically Unlikely Edits (MUE)

The most billing units of J9120 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.5 mg.

Practitioner Office & Hospital Outpatient

5 units / day

= 2.5 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

COSMEGEN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Ewing Sarcoma Gestational Trophoblastic Neoplasia Locally Recurrent and Locoregional Solid Malignancies Metastatic Nonseminomatous Testicular Cancer Rhabdomyosarcoma Wilms Tumor

Drug Class

Actinomycin [EPC]Nucleic Acid Synthesis Inhibitors [MoA]Protein Synthesis Inhibitors [MoA]

Frequently Asked Questions

Is there an available Cosmegen billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for COSMEGEN.

Are there any available Cosmegen patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for COSMEGEN.

Where can I find Cosmegen prescribing information?

COSMEGEN prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Cosmegen side effect information?

Our team has not yet identified a source of side effects information for COSMEGEN. Please check back in a few weeks.

Does billing COSMEGEN require JZ/JW wastage modifiers?

CMS has identified COSMEGEN(J9120) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.