CIDOFOVIR J Code: J0740

Drug & Product Overview

HCPCS Descriptor Injection, cidofovir, 375 mg

HCPCS Added Date January 1, 1998

Manufacturer Multiple Manufacturers

Route of Administration Intravenous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection, Solution

About CIDOFOVIR

Cidofovir is a medication aligned to the HCPCS J Code: J0740 for billing, pricing, and reimbursement purposes in the United States. Classified under Antiviral, it is administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: This drug is used with probenecid to treat a certain viral eye infection (retinitis due to cytomegalovirus-CMV) in people with AIDS. It lowers your risk of blindness and other vision problems. Cidofovir belongs to a class of drugs known as antivirals. It works by stopping the growth of the virus. Cidofovir is not a cure for CMV retinitis, and your disease may still worsen during and after treatment.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
23155-0216-31	Cidofovir Dihydrate	Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.	1	375 MG / 5 ML
67457-0210-05	Cidofovir	Mylan Institutional LLC	1	375 MG / 5 ML

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CIDOFOVIR Pricing & Reimbursement

J0740 Private Payer Reimbursement

$529.81 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

CIDOFOVIR CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Cidofovir (J0740) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

CIDOFOVIR Medically Unlikely Edits (MUE)

The most billing units of J0740 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 375 mg.

Practitioner Office & Hospital Outpatient

2 units / day

= 750 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

CIDOFOVIR Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

CMV retinitis

Drug Class

Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]DNA Polymerase Inhibitors [MoA]Nucleoside Analog [EXT]

Frequently Asked Questions

Is there an available Cidofovir billing and coding guide?

We have not yet identified a manufacturer source of Cidofovir billing and coding information.

Are there any available Cidofovir patient assistance programs?

Our team did not identify a source for Cidofovir patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Cidofovir prescribing information?

Our team is still working to identify a prescribing information source for CIDOFOVIR

Where can I find Cidofovir side effect information?

Our team has not yet identified a source of side effects information for CIDOFOVIR. Please check back in a few weeks.

Does billing CIDOFOVIR require JZ/JW wastage modifiers?

CMS has identified CIDOFOVIR(J0740) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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