BOTOX J Code: J0585

Drug & Product Overview

HCPCS Descriptor Injection, onabotulinumtoxina, 1 unit

HCPCS Added Date January 1, 1991

Manufacturer Allergan

Route of Administration Intradermal, Intramuscular

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution

About BOTOX

Botox is a medication aligned to the HCPCS J Code: J0585 for billing, pricing, and reimbursement purposes in the United States. This Neurology medication is administered via the intradermal or intramuscular routes and manufactured by Allergan.

According to CMS Drug Use Information: There are different types of botulinum toxin products (toxin A and B) with different uses (eye problems, muscle stiffness/spasms, migraines, cosmetic, overactive bladder). Different brands of this medication deliver different amounts of medication. Your doctor will choose the correct product for you. Botulinum toxin is used to treat certain eye disorders such as crossed eyes (strabismus) and uncontrolled blinking (blepharospasm), to treat muscle stiffness/spasms or movement disorders (such as cervical dystonia, torticollis), and to reduce the cosmetic appearance of wrinkles or vertical neck bands connecting the jaw and neck (platysma bands). It is also used to prevent headaches in people with very frequent migraines. Botulinum toxin relaxes muscle by blocking the release of a chemical called acetylcholine. Botulinum toxin is also used to treat overactive bladder by patients who do not respond to or who cannot tolerate the side effects of other medications. It helps to reduce leaking of urine, feeling of needing to urinate right away, and frequent trips to the bathroom. It is also used to treat severe underarm sweating and drooling/excess saliva. Botulinum toxin works by blocking the chemicals that turn on the sweat and salivary glands. Botulinum toxin is not a cure, and your symptoms will gradually return as the medication wears off.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00023-1145-01	Botox	Allergan, Inc.	100	Botox Intradermal Inje ction 100 [USP'U… Login for More
00023-3919-50	BOTOX Cosmetic	Allergan, Inc.	50	BOTOX Cosmetic Intramu scular Injection… Login for More
00023-3921-02	Botox	Allergan, Inc.	200	Botox Intradermal Inje ction 200 [USP'U… Login for More
00023-9232-01	BOTOX Cosmetic	Allergan, Inc.	100	BOTOX Cosmetic Intramu scular Injection… Login for More

Login for the full NDC crosswalk View pricing, complete NDC-to-HCPCS alignments, and package details.

Login →

BOTOX Pricing & Reimbursement

J0585 Private Payer Reimbursement

$6.33 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

BOTOX CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

JW / JZ modifiers apply

CMS has identified Botox (J0585) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

BOTOX Medically Unlikely Edits (MUE)

The most billing units of J0585 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 unit.

Practitioner Office & Hospital Outpatient

800 units / day

= 800 unit per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

BOTOX Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Blepharospasm Cervical Dystonia Chronic Migraine Detrusor Overactivity associated with a Neurologic Condition Neurogenic Detrusor Overactivity Overactive Bladder Primary Axillary Hyperhidrosis Spasticity Strabismus forehead lines glabellar lines lateral canthal lines platysma bands

Drug Class

Acetylcholine Release Inhibitor [EPC]Acetylcholine Release Inhibitors [MoA]Neuromuscular Blockade [PE]Neuromuscular Blocker [EPC]

Frequently Asked Questions

Is there an available Botox billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for BOTOX.

Are there any available Botox patient assistance programs?

BOTOX patient assistance information can be found through Allergan. Visit Here →

Where can I find Botox prescribing information?

BOTOX prescribing information can be found at the link below: Visit Here →

Where can I find Botox side effect information?

Our team has not yet identified a source of side effects information for BOTOX. Please check back in a few weeks.

Does billing BOTOX require JZ/JW wastage modifiers?

CMS has identified BOTOX(J0585) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.