AVONEX Q Code: Q3027

Self-Administered Drug Exclusion 5 Medicare Administrative Contractors list Q3027 as usually self-administered and exclude it from Part B coverage in their jurisdictions. Check the article for your MAC before billing: CGS, Noridian (A53032), Noridian (A53033), Palmetto, Wellpoint Federal, WPS · All SAD lists →

Drug & Product Overview

HCPCS Descriptor Injection, interferon beta-1a, 1 mcg for intramuscular use

HCPCS Added Date January 1, 2014

Manufacturer Biogen

Route of Administration Intramuscular

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Kit

About AVONEX

Avonex is a medication aligned to the HCPCS Q Code: Q3027 for billing, pricing, and reimbursement purposes in the United States. It is a Neurology drug administered via the intramuscular route and manufactured by Biogen.

According to CMS Drug Use Information: This medication is used to treat multiple sclerosis (MS). Interferon is not a cure for MS, but it may help to slow disease worsening and decrease flare-ups of symptoms (such as balance problems, numbness, or weakness).

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

2 NDC packages are crosswalked to Q3027. Package detail is available to logged-in subscribers.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
•••••-••••-•• Log in to view	AVONEX
	AVONEX

Login to view 2 NDC packages View pricing, complete NDC-to-HCPCS alignments, and package details.

AVONEX Pricing & Reimbursement

Q3027 Private Payer Reimbursement

$72.46 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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AVONEX CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

JW / JZ modifiers apply

CMS has identified Avonex (Q3027) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

AVONEX Medically Unlikely Edits (MUE)

The most billing units of Q3027 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mcg.

Practitioner Office & Hospital Outpatient

30 units / day

= 30 mcg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

AVONEX Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

relapsing forms of multiple sclerosis

Frequently Asked Questions

Is there an available Avonex billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for AVONEX.

Are there any available Avonex patient assistance programs?

AVONEX patient assistance information can be found through Biogen. Visit Here →

Where can I find Avonex prescribing information?

AVONEX prescribing information can be found at the link below: Visit Here →

Where can I find Avonex side effect information?

Information regarding AVONEX's side effects can be found at MedlinePlus Visit Here →

Does billing AVONEX require JZ/JW wastage modifiers?

CMS has identified AVONEX(Q3027) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.