Home Drug Codes J Codes J0461 · ATROPINE SULFATE
Updated July 1st, 2026

ATROPINE SULFATE J Code: J0461

Injection, atropine sulfate, 0.01 mg

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Q4 2026 Medicare Payment Limit for J0461, effective October 1, 2026: $0.104 per HCPCS billing unit, down 7.1% from $0.112. From CMS's final file.

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Medicare Payment Limit ?
$0.112
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
17
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Drug & Product Overview

HCPCS Descriptor Injection, atropine sulfate, 0.01 mg
HCPCS Added Date January 1, 2010
Manufacturer Multiple Manufacturers
Route of Administration Intravenous
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injection | Injection, Solution | Not Available

About ATROPINE SULFATE

Atropine Sulfate is a medication aligned to the HCPCS J Code: J0461 for billing, pricing, and reimbursement purposes in the United States. Classified under Cardiology, it is administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 17 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00409-1630-10 Atropine Sulfate Hospira, Inc. 1000 1 MG / 10 ML
00409-4910-34 Atropine Sulfate Pfizer Inc 500 0.5 MG / 5 ML
16729-0484-45 Atropine Sulfate Accord Healthcare, Inc., 1000 1 MG / 10 ML
50090-3138-00 Atropine Sulfate A-S Medication Solutions 1000 1 MG / 10 ML
64253-0400-91 Atropine Sulfate Medefil, Inc. 1000 1 MG / 10 ML
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ATROPINE SULFATE
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ATROPINE SULFATE Pricing & Reimbursement

J0461 Private Payer Reimbursement
$0.33 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Atropine Sulfate 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J0461 Generic Code (Multiple Manufacturers) Atropine Sulfate Injection, atropine sulfate, 0.01 mg
J0462 Generic Code (Multiple Manufacturers) Atropine Sulfate Injection, atropine sulfate, not therapeutically equivalent to j0461, 0.01 mg
J0463 Generic Code (Multiple Manufacturers) Atropine Sulfate Injection, atropine sulfate (fresenius and therapeutically equivalent), 0.01 mg

ATROPINE SULFATE CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular
96374 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug
Not on the CMS JW / JZ list

CMS does not include Atropine Sulfate (J0461) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0461. Wastage billing guide →

ATROPINE SULFATE Medically Unlikely Edits (MUE)

The most billing units of J0461 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.01 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office
200 units / day
= 2 mg per day
Hospital Outpatient
800 units / day
= 8 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

ATROPINE SULFATE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Antidote to cholinesterase inhibitors (organophosphate nerve agents/insecticides) Antidote to muscarine in mushroom poisoning Antidote to organophosphate pesticides Antimuscarinic (salivation/bronchial secretion reduction, antispasmodic, vagal suppression) Antisialagogue or antivagal Arrhythmias Bradyasystolic cardiac arrest Cholinergic adjunct (curariform block) Gastrointestinal radiography (hypotonic radiography) Organophosphorus or muscarinic mushroom poisoning Preanesthesia (antisialagogue / antiarrhythmic) Preanesthesia (antisialagogue)
Drug Class
Anticholinergic [EPC]Cholinergic Antagonists [MoA]Cholinergic Muscarinic Antagonist [EPC]Cholinergic Muscarinic Antagonists [MoA]

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Frequently Asked Questions

Is there an available Atropine Sulfate billing and coding guide?
We have not yet identified a manufacturer source of Atropine Sulfate billing and coding information.
Are there any available Atropine Sulfate patient assistance programs?
ATROPINE SULFATE patient assistance information can be found through Multiple Manufacturers. Visit Here →
Where can I find Atropine Sulfate prescribing information?
ATROPINE SULFATE prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Atropine Sulfate side effect information?
Our team has not yet identified a source of side effects information for ATROPINE SULFATE. Please check back in a few weeks.
Does billing ATROPINE SULFATE require JZ/JW wastage modifiers?
CMS does not include ATROPINE SULFATE (J0461) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0461. For more information, visit the link below.

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