AMPHADASE J Code: J3470

Drug & Product Overview

HCPCS Descriptor Injection, hyaluronidase, up to 150 units

HCPCS Added Date January 1, 1982

Manufacturer Amphastar Pharmaceuticals

Route of Administration Subcutaneous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection

About AMPHADASE

Amphadase is a medication aligned to the HCPCS J Code: J3470 for billing, pricing, and reimbursement purposes in the United States. Classified under Misc., it is administered via the subcutaneous route and manufactured by Amphastar Pharmaceuticals.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00548-9090-10	Amphadase	Amphastar Pharmaceuticals, Inc.	10	Amphadase Subcutaneous Injection 150 U… Login for More

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AMPHADASE Pricing & Reimbursement

J3470 Private Payer Reimbursement

$32.10 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

AMPHADASE CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

Not on the CMS JW / JZ list

CMS does not include Amphadase (J3470) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3470. Wastage billing guide →

AMPHADASE Medically Unlikely Edits (MUE)

The most billing units of J3470 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 150 units.

Practitioner Office & Hospital Outpatient

3 units / day

= 450 units per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

AMPHADASE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Dispersion and Absorption of Injected Drugs Subcutaneous Fluid Administration Subcutaneous Urography

Drug Class

Endoglycosidase [EPC]Glycoside Hydrolases [CS]

Frequently Asked Questions

Is there an available Amphadase billing and coding guide?

We have not yet identified a manufacturer source of Amphadase billing and coding information.

Are there any available Amphadase patient assistance programs?

Our team did not identify a source for Amphadase patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Amphadase prescribing information?

AMPHADASE prescribing information can be found at the link below: Visit Here →

Where can I find Amphadase side effect information?

Information regarding AMPHADASE's side effects can be found at MedlinePlus Visit Here →

Does billing AMPHADASE require JZ/JW wastage modifiers?

CMS does not include AMPHADASE (J3470) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3470. For more information, visit the link below.

About BuyandBill.com:

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