Home Drug Codes J Codes J2315 · VIVITROL
Updated July 1st, 2026

VIVITROL J Code: J2315

Injection, naltrexone, depot form, 1 mg

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Q4 2026 Medicare Payment Limit for J2315, effective October 1, 2026: $4.537 per HCPCS billing unit, up 0.3% from $4.525. From CMS's final file.

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Medicare Payment Limit ?
$4.525
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$4.525
/ HCPCS billing unit · APC 0759
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Injection, naltrexone, depot form, 1 mg
HCPCS Added Date January 1, 2007
Manufacturer Alkermes
Route of Administration Intramuscular
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Kit

About VIVITROL

Vivitrol is a medication aligned to the HCPCS J Code: J2315 for billing, pricing, and reimbursement purposes in the United States. Classified under Anti-Addiction, it is administered via the intramuscular route and manufactured by Alkermes.

According to CMS Drug Use Information: This medication is used to treat alcohol abuse. It is used only in people who have been able to stop drinking for some time before starting treatment with naltrexone. You should not be drinking when you start naltrexone. It can help people drink less alcohol or stop drinking altogether. Naltrexone works in the brain to decrease the desire to drink. It does not work like some other treatments for alcohol abuse (such as disulfiram). It will not make you sick when taken with alcohol. This medication is also used to prevent relapse to opioid abuse, after opioid detoxification. It works by blocking the action of opioids. This medication must not be used in people currently taking opiates, including methadone. Doing so can cause sudden withdrawal symptoms. Naltrexone belongs to a class of drugs known as opiate antagonists. It is used as part of a complete treatment program for alcohol or opioid abuse (such as counseling, 12-step program, lifestyle changes). Ask your doctor or pharmacist if you should have medication available to treat opioid overdose (such as naloxone, nalmefene). Teach your family or household members about the signs of an opioid overdose and how to treat it.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
65757-0300-01 Vivitrol Alkermes, Inc. 380 Kit
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VIVITROL Pricing & Reimbursement

J2315 Private Payer Reimbursement
$4.20 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

VIVITROL CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular
Not on the CMS JW / JZ list

CMS does not include Vivitrol (J2315) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2315. Wastage billing guide →

VIVITROL Medically Unlikely Edits (MUE)

The most billing units of J2315 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient
380 units / day
= 380 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

VIVITROL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Alcohol dependence Opioid dependence

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Frequently Asked Questions

Is there an available Vivitrol billing and coding guide?
Billing and coding information for VIVITROL can be found through Alkermes. Visit Here →
Are there any available Vivitrol patient assistance programs?
VIVITROL patient assistance information can be found through Alkermes. Visit Here →
Where can I find Vivitrol prescribing information?
VIVITROL prescribing information can be found at the link below: Visit Here →
Where can I find Vivitrol side effect information?
Information regarding VIVITROL's side effects can be found at MedlinePlus Visit Here →
Does billing VIVITROL require JZ/JW wastage modifiers?
CMS does not include VIVITROL (J2315) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2315. For more information, visit the link below.

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