VIVITROL J Code: J2315
Injection, naltrexone, depot form, 1 mg
Q4 2026 Medicare Payment Limit for J2315, effective October 1, 2026: $4.537 per HCPCS billing unit, up 0.3% from $4.525. From CMS's final file.
Drug & Product Overview
About VIVITROL
Vivitrol is a medication aligned to the HCPCS J Code: J2315 for billing, pricing, and reimbursement purposes in the United States. Classified under Anti-Addiction, it is administered via the intramuscular route and manufactured by Alkermes.
According to CMS Drug Use Information: This medication is used to treat alcohol abuse. It is used only in people who have been able to stop drinking for some time before starting treatment with naltrexone. You should not be drinking when you start naltrexone. It can help people drink less alcohol or stop drinking altogether. Naltrexone works in the brain to decrease the desire to drink. It does not work like some other treatments for alcohol abuse (such as disulfiram). It will not make you sick when taken with alcohol. This medication is also used to prevent relapse to opioid abuse, after opioid detoxification. It works by blocking the action of opioids. This medication must not be used in people currently taking opiates, including methadone. Doing so can cause sudden withdrawal symptoms. Naltrexone belongs to a class of drugs known as opiate antagonists. It is used as part of a complete treatment program for alcohol or opioid abuse (such as counseling, 12-step program, lifestyle changes). Ask your doctor or pharmacist if you should have medication available to treat opioid overdose (such as naloxone, nalmefene). Teach your family or household members about the signs of an opioid overdose and how to treat it.
Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.
NDC Code Information
Based on publicly available CMS files. The list of NDCs below is not exhaustive.
| NDC Code | Drug | Manufacturer | Billing Units / Pkg | Package Size |
|---|---|---|---|---|
| 65757-0300-01 | Vivitrol | Alkermes, Inc. | 380 | Kit |
VIVITROL Pricing & Reimbursement
National median reimbursement across major commercial payers.
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The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.
| CPT Code | Description |
|---|---|
| 96372 | Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular |
CMS does not include Vivitrol (J2315) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2315. Wastage billing guide →
VIVITROL Medically Unlikely Edits (MUE)
The most billing units of J2315 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.
MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →
VIVITROL Clinical Information
Indications and drug classification.
This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.
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Frequently Asked Questions
Is there an available Vivitrol billing and coding guide?
Are there any available Vivitrol patient assistance programs?
Where can I find Vivitrol prescribing information?
Where can I find Vivitrol side effect information?
Does billing VIVITROL require JZ/JW wastage modifiers?
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