Multiple Manufacturers


ASP | WAC | AWP at the HCPCS Unit


Multiple Manufacturers

Sylvant HCPCS:


HCPCS Code Descriptor:

Injection, siltuximab, 10 mg


J Code

Sylvant NDCs:

73090-0421-01, 57894-0421-01, 73090-0420-01, 57894-0420-01

Primary Type:


Generic/Specialty Status:


Package Type:


Route of Administration:


Sylvant CPT Codes:

Potential CPT administration codes for Sylvant can be found at the following link.

Potential NDC Listing Errors:

Our team has identified potential listing errors/discrepancies with the following NDCs:

73090-0421-01, 57894-0421-01, 57894-0420-01

About Sylvant:

SYLVANT is a medication manufactured by multiple manufacturers and aligned to the J Code: J2860. SYLVANT is administered via the intravenous route of administration.

Sylvant is a drug that is indicated for the treatment of Multicentric Castleman's Disease, or MCD, a rare disease that causes the body to produce too much of one type of white blood cell. Sylvant is thought to work by inhibiting the growth of a protein in the body called interleukin-6 or IL-6. IL-6 can cause an overgrowth of cells in the lymph system when present in high levels. Sylvant is not approved for patients with HIV or human herpesvirus-8.


J2860 Added Date:

January 1, 2016

J2860 Effective Date:

January 1, 2016

J2860 Termination Date:

HCPCS Active

We have not yet identified a manufacturer source of Sylvant billing and coding information.
Sylvant patient assistance information can be found through Eusa Patient Connect at the URL:
SYLVANT prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date.
Our team has not yet identified a source of side effects information for SYLVANT. Please check back in a few weeks.