Rybrevant J Code: J9061

Drug & Product Overview

HCPCS Descriptor Injection, amivantamab-vmjw, 2 mg

HCPCS Added Date January 1, 2022

Manufacturer Janssen

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection

About Rybrevant

Rybrevant is a medication aligned to the HCPCS J Code: J9061 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the intravenous route and manufactured by Janssen.

According to CMS Drug Use Information: Amivantamab is used to treat a certain type of lung cancer (non-small cell lung cancer - NSCLC). It works by slowing or stopping the growth of cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 1 of 2 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
57894-0501-01	Rybrevant	Janssen Biotech, Inc.	175	350 MG
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Rybrevant Pricing & Reimbursement

J9061 Private Payer Reimbursement

$23.26 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

Rybrevant Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 14.28%

Avg. Days to File 8.5days

Avg. Days to Pay 26.6days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J9061 claims analytics on FocalPoint →

Rybrevant CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Rybrevant (J9061) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

Rybrevant Medically Unlikely Edits (MUE)

The most billing units of J9061 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 2 mg.

Practitioner Office & Hospital Outpatient

1,050 units / day

= 2,100 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

Rybrevant Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

NSCLC with EGFR Exon 19 Deletions or Exon 21 L858R Substitution Mutations NSCLC with EGFR Exon 20 Insertion Mutations

Frequently Asked Questions

Is there an available Rybrevant billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for Rybrevant.

Are there any available Rybrevant patient assistance programs?

Rybrevant patient assistance information can be found through Janssen. Visit Here →

Where can I find Rybrevant prescribing information?

Rybrevant prescribing information can be found at the link below: Visit Here →

Where can I find Rybrevant side effect information?

Information regarding Rybrevant's side effects can be found at MedlinePlus Visit Here →

Does billing Rybrevant require JZ/JW wastage modifiers?

CMS has identified Rybrevant(J9061) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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