Home Drug Codes A Codes A9595 · PYLARIFY
Updated July 1st, 2026

PYLARIFY A Code: A9595

Piflufolastat f 18 (pylarify), diagnostic, 1 millicurie

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Medicare Payment Limit ?
Not published
CMS publishes none for Q3 2026
APC Payment Limit ?
$346.49
/ HCPCS billing unit · APC 9430
ASP ?
No current ASP
Not available for Q3 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
2
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Drug & Product Overview

HCPCS Descriptor Piflufolastat f 18 (pylarify), diagnostic, 1 millicurie
HCPCS Added Date January 1, 2022
Manufacturer Progenics Pharmaceuticals, Inc
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Multi-Dose
Dosage Form Injection

About PYLARIFY

Pylarify is a medication aligned to the HCPCS A Code: A9595 for billing, pricing, and reimbursement purposes in the United States. It is an Imaging/Radiopharmaceutical drug administered via the intravenous route and manufactured by Progenics Pharmaceuticals, Inc.

Manufacturers, reach out to us to add more information.

NDC Code Information

2 NDC packages are crosswalked to A9595. Package detail is available to logged-in subscribers.

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PYLARIFY Pricing & Reimbursement

A9595 Private Payer Reimbursement
$631.30 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Piflufolastat F-18 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
A9595 Progenics Pharmaceuticals, Inc Piflufolastat F-18 Piflufolastat f 18 (pylarify), diagnostic, 1 millicurie

PYLARIFY CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
78811 Positron emission tomography (PET) imaging; limited area (eg, chest, head/neck)
78812 Positron emission tomography (PET) imaging; skull base to mid-thigh
78813 Login for More Tumor imaging, positron emission tomography (PET) with concurrently acquired computed tomography (CT) for attenuation correction and anatomical localization; whole body. Login for More
78814 Login for More Tumor imaging, positron emission tomography (PET) with concurrently acquired computed tomography (CT) for attenuation correction and anatomical localization; whole body. Login for More
78815 Login for More Positron emission tomography (PET) with concurrently acquired computed tomography (CT) for attenuation correction and anatomical localization; skull base to mid-thigh. Login for More
78816 Login for More Positron emission tomography (PET) imaging; with concurrently acquired computed tomography (CT) for attenuation correction and anatomical localization, whole body. Login for More
Not on the CMS JW / JZ list

CMS does not include Pylarify (A9595) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing A9595. Wastage billing guide →

PYLARIFY Medically Unlikely Edits (MUE)

The most billing units of A9595 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 millicurie.

Practitioner Office & Hospital Outpatient
10 units / day
= 10 millicurie per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

millicurie Enter a dose to see how many billing units it is and whether it is under the limit.

PYLARIFY Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Prostate cancer with suspected metastasis who are candidates for initial definitive therapy Prostate cancer with suspected recurrence based on elevated serum PSA level
Drug Class
Positron Emitting Activity [MoA]Radioactive Diagnostic Agent [EPC]

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Frequently Asked Questions

Is there an available Pylarify billing and coding guide?
Billing and coding information for PYLARIFY can be found through Lantheus. Visit Here →
Are there any available Pylarify patient assistance programs?
PYLARIFY patient assistance information can be found through Lantheus. Visit Here →
Where can I find Pylarify prescribing information?
PYLARIFY prescribing information can be found at the link below: Visit Here →
Where can I find Pylarify side effect information?
Our team has not yet identified a source of side effects information for PYLARIFY. Please check back in a few weeks.
Does billing PYLARIFY require JZ/JW wastage modifiers?
CMS does not include PYLARIFY (A9595) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing A9595. For more information, visit the link below.

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