PROGESTERONE J Code: J2675

Drug & Product Overview

HCPCS Descriptor Injection, progesterone, per 50 mg

HCPCS Added Date January 1, 1986

Manufacturer Multiple Manufacturers

Route of Administration Intramuscular

Generic Status Multi-Source; Generic

Dosage Type Multi-Dose

Dosage Form Injection | Injection, Solution

About PROGESTERONE

Progesterone is a medication aligned to the HCPCS J Code: J2675 for billing, pricing, and reimbursement purposes in the United States. Classified under Fertility, it is administered via the intramuscular route and manufactured by multiple companies.

According to CMS Drug Use Information: Progesterone is a type of hormone (progestin). This medication is similar to the progesterone that your body naturally makes. It is given to replace the hormone when your body is not making enough of it. In women who are not pregnant and have not gone through menopause, this medication is used to restore normal menstrual periods that have stopped for several months (amenorrhea). It is also used to treat abnormal bleeding from the uterus that is due to low hormone levels and not other causes (such as fibroids, cancer of the uterus). Progesterone must not be used to test for pregnancy.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00143-9725-01	Progesterone	Hikma Pharmaceuticals USA Inc.	10	50 MG
00591-3128-79	Progesterone	Actavis Pharma, Inc.	10	500 MG / 10 ML
55150-0306-10	Progesterone	Eugia Us Llc	10	500 MG / 10 ML
63323-0261-10	Progesterone	Fresenius Kabi USA, LLC	10	500 MG / 10 ML
70700-0286-22	Progesterone	XIROMED, LLC	10	500 MG / 10 ML

Login for the full NDC crosswalk View pricing, complete NDC-to-HCPCS alignments, and package details.

Login →

PROGESTERONE Pricing & Reimbursement

J2675 Private Payer Reimbursement

$1.11 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

PROGESTERONE CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

Not on the CMS JW / JZ list

CMS does not include Progesterone (J2675) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2675. Wastage billing guide →

PROGESTERONE Medically Unlikely Edits (MUE)

The most billing units of J2675 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 50 mg.

Practitioner Office & Hospital Outpatient

1 unit / day

= 50 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

PROGESTERONE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Abnormal uterine bleeding Abnormal uterine bleeding due to hormonal imbalance Amenorrhea

Drug Class

Progesterone [CS]Progesterone [EPC]

Frequently Asked Questions

Is there an available Progesterone billing and coding guide?

We have not yet identified a manufacturer source of Progesterone billing and coding information.

Are there any available Progesterone patient assistance programs?

Our team did not identify a source for Progesterone patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Progesterone prescribing information?

Our team is still working to identify a prescribing information source for PROGESTERONE

Where can I find Progesterone side effect information?

Our team has not yet identified a source of side effects information for PROGESTERONE. Please check back in a few weeks.

Does billing PROGESTERONE require JZ/JW wastage modifiers?

CMS does not include PROGESTERONE (J2675) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2675. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.