Home Drug Codes S Codes S5550 · HUMULIN R U-500
Updated July 1st, 2026

HUMULIN R U-500 S Code: S5550

Insulin, rapid onset, 5 units

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Medicare Payment Limit ?
Not published
CMS publishes none for Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
No current ASP
Not available for Q3 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Insulin, rapid onset, 5 units
HCPCS Added Date October 1, 2003
Manufacturer Eli Lilly
Route of Administration Subcutaneous
Generic Status Single-Source; Branded
Dosage Type Multi-Dose
Dosage Form Injection, Solution

About HUMULIN R U-500

Humulin R U-500 is a medication aligned to the HCPCS S Code: S5550 for billing, pricing, and reimbursement purposes in the United States. This Insulin medication is administered via the subcutaneous route and manufactured by Eli Lilly.

Manufacturers, reach out to us to add more information.

NDC Code Information

1 NDC package is crosswalked to S5550. Package detail is available to logged-in subscribers.

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HUMULIN R U-500 CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular
Not on the CMS JW / JZ list

CMS does not include Humulin R U-500 (S5550) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing S5550. Wastage billing guide →

HUMULIN R U-500 Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Diabetes mellitus
Drug Class
Insulin [CS]Insulin [EPC]

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Frequently Asked Questions

Is there an available Humulin R U-500 billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for HUMULIN R U-500.
Are there any available Humulin R U-500 patient assistance programs?
HUMULIN R U-500 patient assistance information can be found through Eli Lilly and Company. Visit Here →
Where can I find Humulin R U-500 prescribing information?
HUMULIN R U-500 prescribing information can be found at the link below: Visit Here →
Where can I find Humulin R U-500 side effect information?
Information regarding HUMULIN R U-500's side effects can be found at MedlinePlus Visit Here →
Does billing HUMULIN R U-500 require JZ/JW wastage modifiers?
CMS does not include HUMULIN R U-500 (S5550) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing S5550. For more information, visit the link below.

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