Home Drug Codes J Codes J9225 · HISTRELIN
Updated July 1st, 2026

HISTRELIN J Code: J9225

Histrelin implant (vantas), 50 mg

Login to unlock all benchmarks
Medicare Payment Limit ?
Not published
CMS publishes none for Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
No current ASP
Not available for Q3 2026
WAC · AWP ?
$•••.••
Login to view
NDCs Crosswalked ?
View NDC crosswalk →

Drug & Product Overview

HCPCS Descriptor Histrelin implant (vantas), 50 mg
HCPCS Added Date January 1, 2006
Manufacturer Endo Pharmaceuticals
Route of Administration Subcutaneous
Generic Status Single-Source; Branded

About HISTRELIN

Histrelin is a medication aligned to the HCPCS J Code: J9225 for billing, pricing, and reimbursement purposes in the United States. This Oncology medication is administered via the subcutaneous route and manufactured by Endo Pharmaceuticals.

Manufacturers, reach out to us to add more information.

NDC Code Information

No NDC packages are aligned to J9225 in publicly available CMS files.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
No public NDC alignments
Login for the full NDC crosswalk View pricing, complete NDC-to-HCPCS alignments, and package details.
Login →

HISTRELIN Pricing & Reimbursement

J9225 Private Payer Reimbursement
$5,055.58 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

HISTRELIN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96402 Chemotherapy administration, subcutaneous or intramuscular; hormonal anti-neoplastic
Not on the CMS JW / JZ list

CMS does not include Histrelin (J9225) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9225. Wastage billing guide →

HISTRELIN Medically Unlikely Edits (MUE)

The most billing units of J9225 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 50 mg.

Practitioner Office & Hospital Outpatient
1 unit / day
= 50 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

Login for BuyandBill.com Analytics

Unlock deeper insights with BuyandBill’s Comparative Report!

  • Compare ASP, WAC, and AWP across drugs.
  • Visualize Drug Price Movement Over Time
  • Tailor reports to drug class, manufacturer, or HCPCS Code.
  • Compare Biosimilar and 505(b)(2) products.

Frequently Asked Questions

Is there an available Histrelin billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for Histrelin. Please reach out to us if this is a mistake.
Are there any available Histrelin patient assistance programs?
HISTRELIN patient assistance information can be found through Endo Pharmaceuticals. Visit Here →
Where can I find Histrelin prescribing information?
No available source of prescribing information for Histrelin
Where can I find Histrelin side effect information?
A link for Histrelin side effect information is not available.
Does billing Histrelin require JZ/JW wastage modifiers?
CMS does not include HISTRELIN (J9225) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9225. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.