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Updated July 1st, 2026

CYTAL WOUND MATRIX Q Code: Q4166

Cytal, per square centimeter (add-on, list separately in addition to primary procedure)

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Medicare Payment Limit ?
Not published
CMS publishes none for Q3 2026
APC Payment Limit ?
$127.14
/ HCPCS billing unit · APC 6001
ASP ?
No current ASP
Not available for Q3 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
16
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Drug & Product Overview

HCPCS Descriptor Cytal, per square centimeter (add-on, list separately in addition to primary procedure)
HCPCS Added Date January 1, 2017
Manufacturer Multiple Manufacturers
Route of Administration Topical
Generic Status Single-Source; Branded

About CYTAL WOUND MATRIX

Cytal Wound Matrix is a medication aligned to the HCPCS Q Code: Q4166 for billing, pricing, and reimbursement purposes in the United States. This Wound Care medication is administered via the topical route and manufactured by multiple companies.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

16 NDC packages are crosswalked to Q4166. Package detail is available to logged-in subscribers.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
•••••-••••-•• Log in to view CYTAL WOUND MATRIX
CYTAL WOUND MATRIX
CYTAL WOUND MATRIX
CYTAL WOUND MATRIX
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CYTAL WOUND MATRIX CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
15271 Application of skin substitute graft to trunk, arms, legs, total wound surface area up to 100 sq cm; first 25 sq cm or less wound surface area.
15272 Application of skin substitute graft to trunk, arms, legs, total wound surface area up to 100 sq cm; each additional 25 sq cm wound surface area, or part thereof (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

CMS does not include Cytal Wound Matrix (Q4166) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q4166. Wastage billing guide →

CYTAL WOUND MATRIX Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Partial- and full-thickness wounds Pressure ulcers Venous ulcers Diabetic ulcers Chronic vascular ulcers Tunneled wounds Undermined wounds Surgical wounds (donor sites/grafts; post-Mohs; post-laser; podiatric; wound dehiscence) Trauma wounds (abrasions; lacerations; second-degree burns; skin tears) Draining wounds

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Frequently Asked Questions

Is there an available Cytal Wound Matrix billing and coding guide?
We have not yet identified a manufacturer source of Cytal Wound Matrix billing and coding information.
Are there any available Cytal Wound Matrix patient assistance programs?
Our team did not identify a source for Cytal Wound Matrix patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Cytal Wound Matrix prescribing information?
CYTAL WOUND MATRIX prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Cytal Wound Matrix side effect information?
Our team has not yet identified a source of side effects information for CYTAL WOUND MATRIX. Please check back in a few weeks.
Does billing CYTAL WOUND MATRIX require JZ/JW wastage modifiers?
CMS does not include CYTAL WOUND MATRIX (Q4166) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q4166. For more information, visit the link below.

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