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Updated July 1st, 2026

BREYANZI Q Code: Q2054

Lisocabtagene maraleucel, up to 110 million autologous anti-cd19 car-positive viable t cells, including leukapheresis and dose preparation procedures, per therapeutic dose

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Q4 2026 Medicare Payment Limit for Q2054, effective October 1, 2026: $589,846.771 per HCPCS billing unit, up 1.8% from $579,570.614. From CMS's final file.

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Medicare Payment Limit ?
$579,570.614
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$579,570.614
/ HCPCS billing unit · APC 9413
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Lisocabtagene maraleucel, up to 110 million autologous anti-cd19 car-positive viable t cells, including leukapheresis and dose preparation procedures, per therapeutic dose
HCPCS Added Date October 1, 2021
Manufacturer Bristol Myers Squibb
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Kit

About BREYANZI

Breyanzi is a medication aligned to the HCPCS Q Code: Q2054 for billing, pricing, and reimbursement purposes in the United States. This Oncology medication is administered via the intravenous route and manufactured by Bristol Myers Squibb.

According to CMS Drug Use Information: Lisocabtagene maraleucel is used to treat a certain type of cancer (non-Hodgkin lymphoma). This type of treatment is known as gene therapy. Lisocabtagene maraleucel is made from your own white blood cells and is given only to you. The white blood cells have been changed to have a specific protein (chimeric antigen receptor-CAR) that helps your body slow or stop the growth of certain cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
73153-0900-01 Breyanzi Juno Therapeutics, Inc. 1 Kit
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BREYANZI Pricing & Reimbursement

Q2054 Private Payer Reimbursement
$592,052.72 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

BREYANZI Claims Performance

Claims from Jan 2026 – Aug 2026
Claim Denial Rate 61.11%
Avg. Days to File 28.9days
Avg. Days to Pay 78.6days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore Q2054 claims analytics on FocalPoint →
OnPoint Oncology

BREYANZI CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96413 Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

CMS does not include Breyanzi (Q2054) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q2054. Wastage billing guide →

BREYANZI Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Large B-cell Lymphoma (LBCL) Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Follicular Lymphoma (FL) Mantle Cell Lymphoma (MCL)

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Frequently Asked Questions

Is there an available Breyanzi billing and coding guide?
Billing and coding information for BREYANZI can be found through Bristol Myers Squibb. Visit Here →
Are there any available Breyanzi patient assistance programs?
BREYANZI patient assistance information can be found through Bristol Myers Squibb. Visit Here →
Where can I find Breyanzi prescribing information?
BREYANZI prescribing information can be found at the link below: Visit Here →
Where can I find Breyanzi side effect information?
Information regarding BREYANZI's side effects can be found at MedlinePlus Visit Here →
Does billing BREYANZI require JZ/JW wastage modifiers?
CMS does not include BREYANZI (Q2054) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q2054. For more information, visit the link below.

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