Azacitidine J Code: J9025

Drug & Product Overview

HCPCS Descriptor Injection, azacitidine, 1 mg

HCPCS Added Date January 1, 2006

Manufacturer Multiple Manufacturers

Route of Administration Intravenous, Subcutaneous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution | Not Available

About Azacitidine

Azacitidine is a medication aligned to the HCPCS J Code: J9025 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the intravenous or subcutaneous routes and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used to treat certain types of blood cancers in which the bone marrow does not produce enough healthy blood cells. People with these disorders usually have problems such as infections, anemia, and easy bleeding/bruising. Azacitidine works by helping your bone marrow make healthy blood cells. It also kills abnormal blood cells that have grown too fast and do not work properly. This form of azacitidine should not be used in place of the form taken by mouth.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 23 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00143-9606-01	Azacitidine	Hikma Pharmaceuticals USA Inc.	100	100 MG
00781-3253-94	Azacitidine	Sandoz Inc.	100	100 MG
00781-3491-94	Azacitidine	Sandoz Inc	100	100 MG
16714-0927-01	Azacitidine	NorthStar RxLLC	100	100 MG
16729-0306-10	Azacitidine	Accord Healthcare Inc.	100	100 MG
•••••-••••-•• Log in to view	Azacitidine
	Azacitidine
	Azacitidine

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Azacitidine Pricing & Reimbursement

J9025 Private Payer Reimbursement

$0.90 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

Azacitidine 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J9025	Generic Code (Multiple Manufacturers)	Azacitidine	Injection, azacitidine, 1 mg

Azacitidine Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 6.05%

Avg. Days to File 5.8days

Avg. Days to Pay 21.4days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J9025 claims analytics on FocalPoint →

Azacitidine CPT Administration Codes

CPT Code	Description
96401	Chemotherapy administration, subcutaneous or intramuscular; non-hormonal anti-neoplastic
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Login for More	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure) Login for More

JW / JZ modifiers apply

CMS has identified Azacitidine (J9025) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

Azacitidine Medically Unlikely Edits (MUE)

The most billing units of J9025 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

300 units / day

= 300 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

Azacitidine Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Juvenile Myelomonocytic Leukemia (JMML) Myelodysplastic Syndromes Myelodysplastic Syndromes (MDS)

Drug Class

Nucleic Acid Synthesis Inhibitors [MoA]Nucleoside Metabolic Inhibitor [EPC]

Frequently Asked Questions

Is there an available Azacitidine billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for Azacitidine.

Are there any available Azacitidine patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for Azacitidine.

Where can I find Azacitidine prescribing information?

Azacitidine prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Azacitidine side effect information?

Our team has not yet identified a source of side effects information for Azacitidine. Please check back in a few weeks.

Does billing Azacitidine require JZ/JW wastage modifiers?

CMS has identified Azacitidine(J9025) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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