Home › Drug Codes › C Codes › C9257 · AVASTIN
Updated October 1st, 2026

AVASTIN C Code: C9257

Injection, bevacizumab, 0.25 mg

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Medicare Payment Limit ?
Not published
CMS publishes none for Q4 2026
APC Payment Limit ?
$1.887
/ HCPCS billing unit · APC 1281
ASP ?
No current ASP
Not available for Q4 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
2
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Drug & Product Overview

HCPCS Descriptor Injection, bevacizumab, 0.25 mg
HCPCS Added Date January 1, 2010
Manufacturer Genentech
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Injection, Solution

About AVASTIN

Avastin is a medication aligned to the HCPCS C Code: C9257 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the intravenous route and manufactured by Genentech.

Manufacturers, reach out to us to add more information.

NDC Code Information

2 NDC packages are crosswalked to C9257. Package detail is available to logged-in subscribers.

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AVASTIN Pricing & Reimbursement

C9257 Private Payer Reimbursement
$21.82 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

AVASTIN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96413 Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

CMS does not include Avastin (C9257) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing C9257. Wastage billing guide →

AVASTIN Medically Unlikely Edits (MUE)

The most billing units of C9257 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.25 mg.

Practitioner Office & Hospital Outpatient
10 units / day
= 2.5 mg per day

MAI 2 · Date of Service Edit: Policy. Absolute per-day limit set by policy or regulation; units above it are not payable, and denials are not appealable on medical-necessity grounds. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

AVASTIN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Hepatocellular Carcinoma Metastatic Colorectal Cancer Metastatic Renal Cell Carcinoma Non-Squamous Non-Small Cell Lung Cancer Persistent, Recurrent, or Metastatic Cervical Cancer Recurrent Glioblastoma
Drug Class
Vascular Endothelial Growth Factor Inhibitor [EPC]Vascular Endothelial Growth Factor Inhibitors [MoA]Vascular Endothelial Growth Factor-directed Antibody Interactions [MoA]

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Frequently Asked Questions

Is there an available Avastin billing and coding guide?
Billing and coding information for AVASTIN can be found through Genentech. Visit Here →
Are there any available Avastin patient assistance programs?
AVASTIN patient assistance information can be found through Genentech. Visit Here →
Where can I find Avastin prescribing information?
AVASTIN prescribing information can be found at the link below: Visit Here →
Where can I find Avastin side effect information?
Information regarding AVASTIN's side effects can be found at MedlinePlus Visit Here →
Does billing AVASTIN require JZ/JW wastage modifiers?
CMS does not include AVASTIN (C9257) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing C9257. For more information, visit the link below.

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