ARIXTRA J Code: J1652

Drug & Product Overview

HCPCS Descriptor Injection, fondaparinux sodium, 0.5 mg

HCPCS Added Date January 1, 2003

Manufacturer Multiple Manufacturers

Route of Administration Subcutaneous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection | Injection, Solution | Not Available

About ARIXTRA

Arixtra is a medication aligned to the HCPCS J Code: J1652 for billing, pricing, and reimbursement purposes in the United States. Classified under Hematology, it is administered via the subcutaneous route and manufactured by multiple companies.

According to CMS Drug Use Information: Fondaparinux is used to treat serious blood clots in the legs and/or lungs. It is usually used with another "blood thinner" medication (warfarin). If untreated, blood clots can travel to the lungs, heart, or brain, causing serious (possibly fatal) breathing problems, heart attack, or stroke. This drug may also be used to prevent blood clots after certain surgeries with an increased risk of blood clots (such as hip fracture, abdominal, knee/hip replacement). Fondaparinux is known as a "blood thinner" (anticoagulant). It is a drug similar to heparin that works by blocking certain natural substances in the blood that cause clotting.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 44 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00781-3443-95	Fondaparinux Sodium	Sandoz Inc.	50	2.5 MG / 0.5 ML
55111-0678-02	Fondaparinux Sodium	Dr. Reddy's Laboratories Limited	10	2.5 MG / 0.5 ML
55150-0230-10	Fondaparinux Sodium	Eugia Us Llc	50	2.5 MG / 0.5 ML
67457-0582-10	Fondaparinux Sodium	Mylan Institutional LLC	50	2.5 MG / 0.5 ML
70710-1514-06	fondaparinux sodium	Zydus Pharmaceuticals (USA) Inc.	50	2.5 MG / 0.5 ML
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ARIXTRA Pricing & Reimbursement

J1652 Private Payer Reimbursement

$0.91 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

ARIXTRA CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

JW / JZ modifiers apply

CMS has identified Arixtra (J1652) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

ARIXTRA Medically Unlikely Edits (MUE)

The most billing units of J1652 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.5 mg.

Practitioner Office & Hospital Outpatient

20 units / day

= 10 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

ARIXTRA Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acute Deep Vein Thrombosis Acute Pulmonary Embolism Deep Vein Thrombosis Deep Vein Thrombosis Prophylaxis Venous Thromboembolism

Drug Class

Factor Xa Inhibitor [EPC]Factor Xa Inhibitors [MoA]

Frequently Asked Questions

Is there an available Arixtra billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for ARIXTRA.

Are there any available Arixtra patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for ARIXTRA.

Where can I find Arixtra prescribing information?

ARIXTRA prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Arixtra side effect information?

Our team has not yet identified a source of side effects information for ARIXTRA. Please check back in a few weeks.

Does billing ARIXTRA require JZ/JW wastage modifiers?

CMS has identified ARIXTRA(J1652) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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