APHEXDA J Code: J2277

Drug & Product Overview

HCPCS Descriptor Injection, motixafortide, 0.25 mg

HCPCS Added Date April 1, 2024

Manufacturer BioLineRx

Route of Administration Subcutaneous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution

About APHEXDA

Aphexda is a medication aligned to the HCPCS J Code: J2277 for billing, pricing, and reimbursement purposes in the United States. This Oncology medication is administered via the subcutaneous route and manufactured by BioLineRx.

According to CMS Drug Use Information: Motixafortide is used by people with a certain type of cancer (multiple myeloma) to prepare for stem cell transplant. Stem cells, which are found mainly in the bone marrow, turn into red blood cells, white blood cells, and platelets. Motixafortide is used to help stem cells move from the bone marrow to the bloodstream so that the cells can be collected and stored. The stem cells are then given back to you by infusion after chemotherapy or radiation.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
73441-0062-01	Aphexda	Gamida Cell Inc.	248	62 MG / 1.7 ML
82737-0073-01	Aphexda	BioLineRx USA Inc	248	62 MG / 1.7 ML

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APHEXDA Pricing & Reimbursement

J2277 Private Payer Reimbursement

$27.11 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

APHEXDA CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

APHEXDA Medically Unlikely Edits (MUE)

The most billing units of J2277 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.25 mg.

Practitioner Office & Hospital Outpatient

750 units / day

= 187.5 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

APHEXDA Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

hematopoietic stem cell mobilization for autologous transplantation in multiple myeloma mobilization of hematopoietic stem cells for autologous transplantation in multiple myeloma

Frequently Asked Questions

Is a Aphexda billing and coding guide available?

We have not yet identified a manufacturer source of billing and coding information for Aphexda

Is Aphexda patient assistance information available?

Aphexda patient assistance information can be found through Biolinerx at the URL: https://www.aphexda.com/patient-support-and-resources#biolinerx-connect Visit Here →

Where can I find Aphexda prescribing information?

APHEXDA prescribing information can be found at the link below: Visit Here →

Where can I find Aphexda side effect information?

Our team has not yet identified a source of side effect information for APHEXDA

Does billing APHEXDA require JZ/JW wastage modifiers?

CMS does not include APHEXDA (J2277) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2277. For more information, visit the link below.

About BuyandBill.com:

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