FLUOROURACIL J Code: J9190

Drug & Product Overview

HCPCS Descriptor Injection, fluorouracil, 500 mg

HCPCS Added Date January 1, 1984

Manufacturer Multiple Manufacturers

Route of Administration Intravenous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose, Multi-Dose

Dosage Form Injection, Solution

About FLUOROURACIL

Fluorouracil is a medication aligned to the HCPCS J Code: J9190 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: Fluorouracil is used to treat various types of cancer. It is a chemotherapy drug that is used to slow or stop cancer cell growth.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 33 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
16729-0276-38	Fluorouracil	Accord Healthcare, Inc.	10	5000 MG / 100 ML
25021-0215-98	fluorouracil	Sagent Pharmaceuticals	5	2500 MG / 50 ML
55150-0498-01	Fluorouracil	Eugia Us Llc	5	5000 MG / 100 ML
62332-0751-50	Fluorouracil	Alembic Pharmaceuticals Inc.	5	2500 MG / 50 ML
63323-0117-10	Fluorouracil	Fresenius Kabi USA, LLC	10	500 MG / 10 ML
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FLUOROURACIL Pricing & Reimbursement

J9190 Private Payer Reimbursement

$1.96 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

FLUOROURACIL Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 9.3%

Avg. Days to File 10.7days

Avg. Days to Pay 25.3days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J9190 claims analytics on FocalPoint →

FLUOROURACIL CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

CMS does not include Fluorouracil (J9190) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9190. Wastage billing guide →

FLUOROURACIL Medically Unlikely Edits (MUE)

The most billing units of J9190 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 500 mg.

Practitioner Office & Hospital Outpatient

20 units / day

= 10,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

FLUOROURACIL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Adenocarcinoma of the Breast Adenocarcinoma of the Colon and Rectum Gastric Adenocarcinoma Pancreatic Adenocarcinoma

Drug Class

Nucleic Acid Synthesis Inhibitors [MoA]Nucleoside Metabolic Inhibitor [EPC]

Frequently Asked Questions

Is there an available Fluorouracil billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for FLUOROURACIL.

Are there any available Fluorouracil patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for FLUOROURACIL.

Where can I find Fluorouracil prescribing information?

FLUOROURACIL prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Fluorouracil side effect information?

Our team has not yet identified a source of side effects information for FLUOROURACIL. Please check back in a few weeks.

Does billing FLUOROURACIL require JZ/JW wastage modifiers?

CMS does not include FLUOROURACIL (J9190) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9190. For more information, visit the link below.

About BuyandBill.com:

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